The relationship
Background and aim of the study: Anti-müllerian hormone (AMH) is a dimeric glycoprotein, which is secreted exclusively by granulose cells of primary, preantral, and small antral follicles (4–6 mm). Women with polycystic ovary syndrome (PCOS) have a 2- to 3-fold increase in the serum AMH concentratio...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2016-03-01
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| Series: | Middle East Fertility Society Journal |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1110569014200215 |
| _version_ | 1818319111495614464 |
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| author | Ahmad Mahran |
| author_facet | Ahmad Mahran |
| author_sort | Ahmad Mahran |
| collection | DOAJ |
| description | Background and aim of the study: Anti-müllerian hormone (AMH) is a dimeric glycoprotein, which is secreted exclusively by granulose cells of primary, preantral, and small antral follicles (4–6 mm). Women with polycystic ovary syndrome (PCOS) have a 2- to 3-fold increase in the serum AMH concentration, which corresponds to the 2- to 3-fold increase in the number of small follicles seen in PCOS. The aim of this study was to assess the relationship between AMH and the clinical, biochemical and sonographic parameters in women with PCOS.
Study design: In this prospective observational study, serum AMH was measured in 200 PCOS women attending 2 fertility clinics in Minia, Egypt. The relationship between AMH and the clinical, biochemical and sonographic parameters of PCOS was studied.
Results: AMH levels were found to have significant positive correlation with cycle length (r = 0.706, P < 0.01), modified Ferriman Gallwey (FG) score for hirsutism (r = 0.329, P < 0.01), mean ovarian volume (r = 0.498, P < 0.01), antral follicle count (AFC) (r = 0.963, P < 0.01) and total testosterone (r = 0.272, P < 0.01).
Conclusion: In conclusion, AMH is strongly correlated with the clinical, biochemical and sonographic features of PCOS. |
| first_indexed | 2024-12-13T10:03:55Z |
| format | Article |
| id | doaj.art-bc4328c53f4f414eacba31146149c5cc |
| institution | Directory Open Access Journal |
| issn | 1110-5690 |
| language | English |
| last_indexed | 2024-12-13T10:03:55Z |
| publishDate | 2016-03-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Middle East Fertility Society Journal |
| spelling | doaj.art-bc4328c53f4f414eacba31146149c5cc2022-12-21T23:51:35ZengSpringerOpenMiddle East Fertility Society Journal1110-56902016-03-01211111510.1016/j.mefs.2015.06.003The relationshipAhmad MahranBackground and aim of the study: Anti-müllerian hormone (AMH) is a dimeric glycoprotein, which is secreted exclusively by granulose cells of primary, preantral, and small antral follicles (4–6 mm). Women with polycystic ovary syndrome (PCOS) have a 2- to 3-fold increase in the serum AMH concentration, which corresponds to the 2- to 3-fold increase in the number of small follicles seen in PCOS. The aim of this study was to assess the relationship between AMH and the clinical, biochemical and sonographic parameters in women with PCOS. Study design: In this prospective observational study, serum AMH was measured in 200 PCOS women attending 2 fertility clinics in Minia, Egypt. The relationship between AMH and the clinical, biochemical and sonographic parameters of PCOS was studied. Results: AMH levels were found to have significant positive correlation with cycle length (r = 0.706, P < 0.01), modified Ferriman Gallwey (FG) score for hirsutism (r = 0.329, P < 0.01), mean ovarian volume (r = 0.498, P < 0.01), antral follicle count (AFC) (r = 0.963, P < 0.01) and total testosterone (r = 0.272, P < 0.01). Conclusion: In conclusion, AMH is strongly correlated with the clinical, biochemical and sonographic features of PCOS.http://www.sciencedirect.com/science/article/pii/S1110569014200215Polycystic ovary syndromeAnti-müllerian hormoneModified Ferriman Gallwey scoreMean ovarian volumeAntral follicle count |
| spellingShingle | Ahmad Mahran The relationship Middle East Fertility Society Journal Polycystic ovary syndrome Anti-müllerian hormone Modified Ferriman Gallwey score Mean ovarian volume Antral follicle count |
| title | The relationship |
| title_full | The relationship |
| title_fullStr | The relationship |
| title_full_unstemmed | The relationship |
| title_short | The relationship |
| title_sort | relationship |
| topic | Polycystic ovary syndrome Anti-müllerian hormone Modified Ferriman Gallwey score Mean ovarian volume Antral follicle count |
| url | http://www.sciencedirect.com/science/article/pii/S1110569014200215 |
| work_keys_str_mv | AT ahmadmahran therelationship AT ahmadmahran relationship |