Prolonged abstinence from cocaine or morphine disrupts separable valuations during decision conflict

Neuroeconomic theories suggest that conflict during decision, such as exhibited by relapsing drug addicts who continue drug use despite stated wishes not to, might arise from separable processes in decision making. Here the authors test mice in a foraging task designed to separate these processes an...

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Main Authors: Brian M. Sweis, A. David Redish, Mark J. Thomas
Format: Article
Language:English
Published: Nature Portfolio 2018-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-04967-2
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author Brian M. Sweis
A. David Redish
Mark J. Thomas
author_facet Brian M. Sweis
A. David Redish
Mark J. Thomas
author_sort Brian M. Sweis
collection DOAJ
description Neuroeconomic theories suggest that conflict during decision, such as exhibited by relapsing drug addicts who continue drug use despite stated wishes not to, might arise from separable processes in decision making. Here the authors test mice in a foraging task designed to separate these processes and find that mice show alterations in separable components of decision conflict following abstinence from cocaine versus morphine.
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spelling doaj.art-bc45223822ab4190bb7e126f259586432022-12-21T23:38:50ZengNature PortfolioNature Communications2041-17232018-06-01911910.1038/s41467-018-04967-2Prolonged abstinence from cocaine or morphine disrupts separable valuations during decision conflictBrian M. Sweis0A. David Redish1Mark J. Thomas2Graduate Program in Neuroscience & Medical Scientist Training Program, University of MinnesotaDepartment of Neuroscience, University of MinnesotaDepartment of Neuroscience, University of MinnesotaNeuroeconomic theories suggest that conflict during decision, such as exhibited by relapsing drug addicts who continue drug use despite stated wishes not to, might arise from separable processes in decision making. Here the authors test mice in a foraging task designed to separate these processes and find that mice show alterations in separable components of decision conflict following abstinence from cocaine versus morphine.https://doi.org/10.1038/s41467-018-04967-2
spellingShingle Brian M. Sweis
A. David Redish
Mark J. Thomas
Prolonged abstinence from cocaine or morphine disrupts separable valuations during decision conflict
Nature Communications
title Prolonged abstinence from cocaine or morphine disrupts separable valuations during decision conflict
title_full Prolonged abstinence from cocaine or morphine disrupts separable valuations during decision conflict
title_fullStr Prolonged abstinence from cocaine or morphine disrupts separable valuations during decision conflict
title_full_unstemmed Prolonged abstinence from cocaine or morphine disrupts separable valuations during decision conflict
title_short Prolonged abstinence from cocaine or morphine disrupts separable valuations during decision conflict
title_sort prolonged abstinence from cocaine or morphine disrupts separable valuations during decision conflict
url https://doi.org/10.1038/s41467-018-04967-2
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