Passaging Primary Human Bronchial Epithelia Reduces CFTR-Mediated Fluid Transport and Alters mRNA Expression

Primary human bronchial epithelial cultures (HBECs) are used to study airway physiology, disease, and drug development. HBECs often replicate human airway physiology/pathophysiology. Indeed, in the search for cystic fibrosis (CF) transmembrane conductance regulator (CFTR) therapies, HBECs were seen...

Полное описание

Библиографические подробности
Главные авторы: Tongde Wu, Joe A. Wrennall, Hong Dang, Deborah L. Baines, Robert Tarran
Формат: Статья
Язык:English
Опубликовано: MDPI AG 2023-03-01
Серии:Cells
Предметы:
Online-ссылка:https://www.mdpi.com/2073-4409/12/7/997