Tribolium castaneum defensin 1 kills Moraxella catarrhalis in an in vitro infection model but does not harm commensal bacteria

Tribolium castaneum defensin 1 kills Moraxella catarrhalis in an in vitro infection model but does not harm commensal bacteria

Moraxella catarrhalis is a bacterial pathogen that causes respiratory tract infections in humans. The increasing prevalence of antibiotic-resistant M. catarrhalis strains has created a demand for alternative treatment options. We therefore tested 23 insect antimicrobial peptides (AMPs) for their act...

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Bibliographic Details
Main Authors: Wilhelm Bertrams, Nora S. Lindhauer, Marie Christin Rieke, Anne Paas, Kerstin Hoffmann, Brandon Greene, Alexander Visekruna, Andreas Vilcinskas, Kerstin Seidel, Bernd Schmeck
Format: Article
Language:English
Published: Taylor & Francis Group 2021-12-01
Series:Virulence
Subjects:
antimicrobial peptides
moraxella catarrhalis
macrophages
inflammation
insect
antibiotic resistance
defensin
commensals
Online Access:http://dx.doi.org/10.1080/21505594.2021.1908741

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