Identification and in vitro and in vivo validation of the key role of GSDME in pyroptosis-related genes signature in hepatocellular carcinoma

Identification and in vitro and in vivo validation of the key role of GSDME in pyroptosis-related genes signature in hepatocellular carcinoma

Abstract We used pyroptosis-related genes to establish a risk–score model for prognostic prediction of liver hepatocellular carcinoma (LIHC) patients. A total of 52 pyroptosis-associated genes were identified. Then, data for 374 LIHC patients and 50 normal individuals were acquired from the TCGA dat...

Full description

Bibliographic Details
Main Authors: Xinyi Chen, Mu Yang, Lu Wang, Yuan Wang, Jingyao Tu, Xiao Zhou, Xianglin Yuan
Format: Article
Language:English
Published: BMC 2023-05-01
Series:BMC Cancer
Subjects:
Pyroptosis
GSDME
Liver hepatocellular carcinoma (LIHC)
Prognostic signature
Bioinformatics analysis
Online Access:https://doi.org/10.1186/s12885-023-10850-1

Similar Items

Similar Items