Anakinra Reduces Epileptogenesis, Provides Neuroprotection, and Attenuates Behavioral Impairments in Rats in the Lithium–Pilocarpine Model of Epilepsy

Temporal lobe epilepsy is a widespread chronic disorder that manifests as spontaneous seizures and is often characterized by refractoriness to drug treatment. Temporal lobe epilepsy can be caused by a primary brain injury; therefore, the prevention of epileptogenesis after a primary event is conside...

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Bibliographic Details
Main Authors: Alexandra V. Dyomina, Olga E. Zubareva, Ilya V. Smolensky, Dmitry S. Vasilev, Maria V. Zakharova, Anna A. Kovalenko, Alexander P. Schwarz, Alexander M. Ischenko, Aleksey V. Zaitsev
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/13/11/340