The conservation of human functional variants and their effects across livestock species

An investigation of genetic variants that exist across human and livestock species supports the clear potential of livestock models in providing insights into the mechanisms driving human diseases and traits.

Bibliographic Details
Main Authors: Rongrong Zhao, Andrea Talenti, Lingzhao Fang, Shuli Liu, George Liu, Neil P. Chue Hong, Albert Tenesa, Musa Hassan, James G. D. Prendergast
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03961-1
_version_ 1811208699583135744
author Rongrong Zhao
Andrea Talenti
Lingzhao Fang
Shuli Liu
George Liu
Neil P. Chue Hong
Albert Tenesa
Musa Hassan
James G. D. Prendergast
author_facet Rongrong Zhao
Andrea Talenti
Lingzhao Fang
Shuli Liu
George Liu
Neil P. Chue Hong
Albert Tenesa
Musa Hassan
James G. D. Prendergast
author_sort Rongrong Zhao
collection DOAJ
description An investigation of genetic variants that exist across human and livestock species supports the clear potential of livestock models in providing insights into the mechanisms driving human diseases and traits.
first_indexed 2024-04-12T04:26:00Z
format Article
id doaj.art-bc55ff2b2e5344e790cd39b1eb457332
institution Directory Open Access Journal
issn 2399-3642
language English
last_indexed 2024-04-12T04:26:00Z
publishDate 2022-09-01
publisher Nature Portfolio
record_format Article
series Communications Biology
spelling doaj.art-bc55ff2b2e5344e790cd39b1eb4573322022-12-22T03:48:05ZengNature PortfolioCommunications Biology2399-36422022-09-015111310.1038/s42003-022-03961-1The conservation of human functional variants and their effects across livestock speciesRongrong Zhao0Andrea Talenti1Lingzhao Fang2Shuli Liu3George Liu4Neil P. Chue Hong5Albert Tenesa6Musa Hassan7James G. D. Prendergast8The Roslin Institute, University of Edinburgh, Easter Bush CampusThe Roslin Institute, University of Edinburgh, Easter Bush CampusThe Roslin Institute, University of Edinburgh, Easter Bush CampusWestlake Laboratory of Life Sciences and BiomedicineAnimal Genomics and Improvement Laboratory, Henry A. Wallace Beltsville Agricultural Research Center, Agricultural Research Service, Agricultural Research Service, USDAEPCC, Bayes CentreThe Roslin Institute, University of Edinburgh, Easter Bush CampusThe Roslin Institute, University of Edinburgh, Easter Bush CampusThe Roslin Institute, University of Edinburgh, Easter Bush CampusAn investigation of genetic variants that exist across human and livestock species supports the clear potential of livestock models in providing insights into the mechanisms driving human diseases and traits.https://doi.org/10.1038/s42003-022-03961-1
spellingShingle Rongrong Zhao
Andrea Talenti
Lingzhao Fang
Shuli Liu
George Liu
Neil P. Chue Hong
Albert Tenesa
Musa Hassan
James G. D. Prendergast
The conservation of human functional variants and their effects across livestock species
Communications Biology
title The conservation of human functional variants and their effects across livestock species
title_full The conservation of human functional variants and their effects across livestock species
title_fullStr The conservation of human functional variants and their effects across livestock species
title_full_unstemmed The conservation of human functional variants and their effects across livestock species
title_short The conservation of human functional variants and their effects across livestock species
title_sort conservation of human functional variants and their effects across livestock species
url https://doi.org/10.1038/s42003-022-03961-1
work_keys_str_mv AT rongrongzhao theconservationofhumanfunctionalvariantsandtheireffectsacrosslivestockspecies
AT andreatalenti theconservationofhumanfunctionalvariantsandtheireffectsacrosslivestockspecies
AT lingzhaofang theconservationofhumanfunctionalvariantsandtheireffectsacrosslivestockspecies
AT shuliliu theconservationofhumanfunctionalvariantsandtheireffectsacrosslivestockspecies
AT georgeliu theconservationofhumanfunctionalvariantsandtheireffectsacrosslivestockspecies
AT neilpchuehong theconservationofhumanfunctionalvariantsandtheireffectsacrosslivestockspecies
AT alberttenesa theconservationofhumanfunctionalvariantsandtheireffectsacrosslivestockspecies
AT musahassan theconservationofhumanfunctionalvariantsandtheireffectsacrosslivestockspecies
AT jamesgdprendergast theconservationofhumanfunctionalvariantsandtheireffectsacrosslivestockspecies
AT rongrongzhao conservationofhumanfunctionalvariantsandtheireffectsacrosslivestockspecies
AT andreatalenti conservationofhumanfunctionalvariantsandtheireffectsacrosslivestockspecies
AT lingzhaofang conservationofhumanfunctionalvariantsandtheireffectsacrosslivestockspecies
AT shuliliu conservationofhumanfunctionalvariantsandtheireffectsacrosslivestockspecies
AT georgeliu conservationofhumanfunctionalvariantsandtheireffectsacrosslivestockspecies
AT neilpchuehong conservationofhumanfunctionalvariantsandtheireffectsacrosslivestockspecies
AT alberttenesa conservationofhumanfunctionalvariantsandtheireffectsacrosslivestockspecies
AT musahassan conservationofhumanfunctionalvariantsandtheireffectsacrosslivestockspecies
AT jamesgdprendergast conservationofhumanfunctionalvariantsandtheireffectsacrosslivestockspecies