Myelin in Alzheimer’s disease: culprit or bystander?

Abstract Alzheimer’s disease (AD) is a neurodegenerative disorder with neuronal and synaptic losses due to the accumulation of toxic amyloid β (Αβ) peptide oligomers, plaques, and tangles containing tau (tubulin-associated unit) protein. While familial AD is caused by specific mutations, the sporadi...

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Bibliographic Details
Main Authors: Michel Maitre, Hélène Jeltsch-David, Nwife Getrude Okechukwu, Christian Klein, Christine Patte-Mensah, Ayikoe-Guy Mensah-Nyagan
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Acta Neuropathologica Communications
Subjects:
Online Access:https://doi.org/10.1186/s40478-023-01554-5

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