Myelin in Alzheimer’s disease: culprit or bystander?
Abstract Alzheimer’s disease (AD) is a neurodegenerative disorder with neuronal and synaptic losses due to the accumulation of toxic amyloid β (Αβ) peptide oligomers, plaques, and tangles containing tau (tubulin-associated unit) protein. While familial AD is caused by specific mutations, the sporadi...
Main Authors: | Michel Maitre, Hélène Jeltsch-David, Nwife Getrude Okechukwu, Christian Klein, Christine Patte-Mensah, Ayikoe-Guy Mensah-Nyagan |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-03-01
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Series: | Acta Neuropathologica Communications |
Subjects: | |
Online Access: | https://doi.org/10.1186/s40478-023-01554-5 |
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