JAK2V617F and p53 mutations coexist in erythroleukemia and megakaryoblastic leukemic cell lines
<p>Abstract</p> <p>Background</p> <p>JAK2V617F, a gain-of-function mutant form of tyrosine kinase JAK2, is found in the majority of patients with Ph- myeloproliferative neoplasms (MPNs), a group of chronic hematological diseases that often lead to acute leukemia. The cu...
| Egile Nagusiak: | , , , , |
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| Formatua: | Artikulua |
| Hizkuntza: | English |
| Argitaratua: |
BMC
2012-06-01
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| Saila: | Experimental Hematology & Oncology |
| Gaiak: | |
| Sarrera elektronikoa: | http://www.ehoonline.org/content/1/1/15 |