NR2F2 plays a major role in insulin-induced epithelial-mesenchymal transition in breast cancer cells

NR2F2 plays a major role in insulin-induced epithelial-mesenchymal transition in breast cancer cells

Abstract Background The failure of treatment for breast cancer usually results from distant metastasis in which the epithelial-mesenchymal transition (EMT) plays a critical role. Hyperinsulinemia, the hallmark of Type 2 diabetes mellitus (T2DM), has been regarded as a key risk factor for the progres...

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Bibliographic Details
Main Authors: Baili Xia, Lijun Hou, Huan Kang, Wenhui Chang, Yi Liu, Yanli Zhang, Yi Ding
Format: Article
Language:English
Published: BMC 2020-07-01
Series:BMC Cancer
Subjects:
Breast cancer
NR2F2
Insulin
Epithelial-mesenchymal transition
Migration
Invasion metastasis
Online Access:http://link.springer.com/article/10.1186/s12885-020-07107-6

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