Urine Biomarkers for Prostate Cancer Diagnosis and Progression
Prostate cancer (PCa) can be highly heterogeneous and multifocal, and accurate assessment of the volume, grade, and stage of PCa in situ is not a simple task. Urine has been investigated as a source of PCa biomarkers for over 70 years, and there is now strong evidence that analysis of urine could pr...
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Format: | Article |
Language: | English |
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The Société Internationale d’Urologie (SIU)
2021-05-01
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Series: | Société Internationale d’Urologie Journal |
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Online Access: | https://siuj.org/index.php/siuj/article/view/112/37 |
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author | Jeremy Clark, Rachel Hurst, Mark Simon Winterbone, Hardev Pandha, Antoinette Perry, Sophie McGrath, Richard Morgan, Adele E Connor, Asia C Jordan, Deirdre Winrow, Colin Cooper |
author_facet | Jeremy Clark, Rachel Hurst, Mark Simon Winterbone, Hardev Pandha, Antoinette Perry, Sophie McGrath, Richard Morgan, Adele E Connor, Asia C Jordan, Deirdre Winrow, Colin Cooper |
author_sort | Jeremy Clark, Rachel Hurst, Mark Simon Winterbone, Hardev Pandha, Antoinette Perry, Sophie McGrath, Richard Morgan, Adele E Connor, Asia C Jordan, Deirdre Winrow, Colin Cooper |
collection | DOAJ |
description | Prostate cancer (PCa) can be highly heterogeneous and multifocal, and accurate assessment of the volume, grade, and stage of PCa in situ is not a simple task. Urine has been investigated as a source of PCa biomarkers for over 70 years, and there is now strong evidence that analysis of urine could provide more accurate diagnosis and a better risk stratification that could aid clinical decisions regarding disease surveillance and treatment. Urine diagnostics is a developing area, moving towards multi-omic biomarker integration for improved diagnostic performance. Urine tests developed by strong collaborations between scientists and clinicians have the potential to provide targeted and meaningful data that can guide treatment and improve men’s lives. |
first_indexed | 2024-03-08T18:00:35Z |
format | Article |
id | doaj.art-bc62a7b6e976490f918661f6a40231f9 |
institution | Directory Open Access Journal |
issn | 2563-6499 |
language | English |
last_indexed | 2024-03-08T18:00:35Z |
publishDate | 2021-05-01 |
publisher | The Société Internationale d’Urologie (SIU) |
record_format | Article |
series | Société Internationale d’Urologie Journal |
spelling | doaj.art-bc62a7b6e976490f918661f6a40231f92024-01-02T02:14:38ZengThe Société Internationale d’Urologie (SIU)Société Internationale d’Urologie Journal2563-64992021-05-012315917010.48083/SAWC9585Urine Biomarkers for Prostate Cancer Diagnosis and ProgressionJeremy Clark, Rachel Hurst, Mark Simon Winterbone, Hardev Pandha, Antoinette Perry, Sophie McGrath, Richard Morgan, Adele E Connor, Asia C Jordan, Deirdre Winrow, Colin CooperProstate cancer (PCa) can be highly heterogeneous and multifocal, and accurate assessment of the volume, grade, and stage of PCa in situ is not a simple task. Urine has been investigated as a source of PCa biomarkers for over 70 years, and there is now strong evidence that analysis of urine could provide more accurate diagnosis and a better risk stratification that could aid clinical decisions regarding disease surveillance and treatment. Urine diagnostics is a developing area, moving towards multi-omic biomarker integration for improved diagnostic performance. Urine tests developed by strong collaborations between scientists and clinicians have the potential to provide targeted and meaningful data that can guide treatment and improve men’s lives.https://siuj.org/index.php/siuj/article/view/112/37urinebiomarkersprostate cancer |
spellingShingle | Jeremy Clark, Rachel Hurst, Mark Simon Winterbone, Hardev Pandha, Antoinette Perry, Sophie McGrath, Richard Morgan, Adele E Connor, Asia C Jordan, Deirdre Winrow, Colin Cooper Urine Biomarkers for Prostate Cancer Diagnosis and Progression Société Internationale d’Urologie Journal urine biomarkers prostate cancer |
title | Urine Biomarkers for Prostate Cancer Diagnosis and Progression |
title_full | Urine Biomarkers for Prostate Cancer Diagnosis and Progression |
title_fullStr | Urine Biomarkers for Prostate Cancer Diagnosis and Progression |
title_full_unstemmed | Urine Biomarkers for Prostate Cancer Diagnosis and Progression |
title_short | Urine Biomarkers for Prostate Cancer Diagnosis and Progression |
title_sort | urine biomarkers for prostate cancer diagnosis and progression |
topic | urine biomarkers prostate cancer |
url | https://siuj.org/index.php/siuj/article/view/112/37 |
work_keys_str_mv | AT jeremyclarkrachelhurstmarksimonwinterbonehardevpandhaantoinetteperrysophiemcgrathrichardmorganadeleeconnorasiacjordandeirdrewinrowcolincooper urinebiomarkersforprostatecancerdiagnosisandprogression |