Urine Biomarkers for Prostate Cancer Diagnosis and Progression

Prostate cancer (PCa) can be highly heterogeneous and multifocal, and accurate assessment of the volume, grade, and stage of PCa in situ is not a simple task. Urine has been investigated as a source of PCa biomarkers for over 70 years, and there is now strong evidence that analysis of urine could pr...

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Main Author: Jeremy Clark, Rachel Hurst, Mark Simon Winterbone, Hardev Pandha, Antoinette Perry, Sophie McGrath, Richard Morgan, Adele E Connor, Asia C Jordan, Deirdre Winrow, Colin Cooper
Format: Article
Language:English
Published: The Société Internationale d’Urologie (SIU) 2021-05-01
Series:Société Internationale d’Urologie Journal
Subjects:
Online Access:https://siuj.org/index.php/siuj/article/view/112/37
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author Jeremy Clark, Rachel Hurst, Mark Simon Winterbone, Hardev Pandha, Antoinette Perry, Sophie McGrath, Richard Morgan, Adele E Connor, Asia C Jordan, Deirdre Winrow, Colin Cooper
author_facet Jeremy Clark, Rachel Hurst, Mark Simon Winterbone, Hardev Pandha, Antoinette Perry, Sophie McGrath, Richard Morgan, Adele E Connor, Asia C Jordan, Deirdre Winrow, Colin Cooper
author_sort Jeremy Clark, Rachel Hurst, Mark Simon Winterbone, Hardev Pandha, Antoinette Perry, Sophie McGrath, Richard Morgan, Adele E Connor, Asia C Jordan, Deirdre Winrow, Colin Cooper
collection DOAJ
description Prostate cancer (PCa) can be highly heterogeneous and multifocal, and accurate assessment of the volume, grade, and stage of PCa in situ is not a simple task. Urine has been investigated as a source of PCa biomarkers for over 70 years, and there is now strong evidence that analysis of urine could provide more accurate diagnosis and a better risk stratification that could aid clinical decisions regarding disease surveillance and treatment. Urine diagnostics is a developing area, moving towards multi-omic biomarker integration for improved diagnostic performance. Urine tests developed by strong collaborations between scientists and clinicians have the potential to provide targeted and meaningful data that can guide treatment and improve men’s lives.
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spelling doaj.art-bc62a7b6e976490f918661f6a40231f92024-01-02T02:14:38ZengThe Société Internationale d’Urologie (SIU)Société Internationale d’Urologie Journal2563-64992021-05-012315917010.48083/SAWC9585Urine Biomarkers for Prostate Cancer Diagnosis and ProgressionJeremy Clark, Rachel Hurst, Mark Simon Winterbone, Hardev Pandha, Antoinette Perry, Sophie McGrath, Richard Morgan, Adele E Connor, Asia C Jordan, Deirdre Winrow, Colin CooperProstate cancer (PCa) can be highly heterogeneous and multifocal, and accurate assessment of the volume, grade, and stage of PCa in situ is not a simple task. Urine has been investigated as a source of PCa biomarkers for over 70 years, and there is now strong evidence that analysis of urine could provide more accurate diagnosis and a better risk stratification that could aid clinical decisions regarding disease surveillance and treatment. Urine diagnostics is a developing area, moving towards multi-omic biomarker integration for improved diagnostic performance. Urine tests developed by strong collaborations between scientists and clinicians have the potential to provide targeted and meaningful data that can guide treatment and improve men’s lives.https://siuj.org/index.php/siuj/article/view/112/37urinebiomarkersprostate cancer
spellingShingle Jeremy Clark, Rachel Hurst, Mark Simon Winterbone, Hardev Pandha, Antoinette Perry, Sophie McGrath, Richard Morgan, Adele E Connor, Asia C Jordan, Deirdre Winrow, Colin Cooper
Urine Biomarkers for Prostate Cancer Diagnosis and Progression
Société Internationale d’Urologie Journal
urine
biomarkers
prostate cancer
title Urine Biomarkers for Prostate Cancer Diagnosis and Progression
title_full Urine Biomarkers for Prostate Cancer Diagnosis and Progression
title_fullStr Urine Biomarkers for Prostate Cancer Diagnosis and Progression
title_full_unstemmed Urine Biomarkers for Prostate Cancer Diagnosis and Progression
title_short Urine Biomarkers for Prostate Cancer Diagnosis and Progression
title_sort urine biomarkers for prostate cancer diagnosis and progression
topic urine
biomarkers
prostate cancer
url https://siuj.org/index.php/siuj/article/view/112/37
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