AKTIP interacts with ESCRT I and is needed for the recruitment of ESCRT III subunits to the midbody.

AKTIP interacts with ESCRT I and is needed for the recruitment of ESCRT III subunits to the midbody.

To complete mitosis, the bridge that links the two daughter cells needs to be cleaved. This step is carried out by the endosomal sorting complex required for transport (ESCRT) machinery. AKTIP, a protein discovered to be associated with telomeres and the nuclear membrane in interphase cells, shares...

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Bibliographic Details
Main Authors: Chiara Merigliano, Romina Burla, Mattia La Torre, Simona Del Giudice, Hsiangling Teo, Chong Wai Liew, Alexandre Chojnowski, Wah Ing Goh, Yolanda Olmos, Klizia Maccaroni, Maria Giubettini, Irene Chiolo, Jeremy G Carlton, Domenico Raimondo, Fiammetta Vernì, Colin L Stewart, Daniela Rhodes, Graham D Wright, Brian E Burke, Isabella Saggio
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-08-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1009757

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