Photoporation-mediated spatial intracellular delivery of stem cell-derived cardiomyocytes

Human induced pluripotent stem cell-derived cardiomyocytes (iPSCCMs) are promising candidates for disease modeling and therapeutic purposes, however, non-viral intracellular delivery in these cells remains challenging. Gold nanoparticle (AuNP)-sensitized photoporation creates transient pores in the...

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Bibliographic Details
Main Authors: Laurens Léger, Chloë De Clercq, Jeffrey Aalders, Kiara Van Acker-Verberckt, Kevin Braeckmans, Jolanda van Hengel
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:MethodsX
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2215016124000037