DNA Methylation Targeting: The DNMT/HMT Crosstalk Challenge

DNA Methylation Targeting: The DNMT/HMT Crosstalk Challenge

Chromatin can adopt a decondensed state linked to gene transcription (euchromatin) and a condensed state linked to transcriptional repression (heterochromatin). These states are controlled by epigenetic modulators that are active on either the DNA or the histones and are tightly associated to each o...

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Bibliographic Details
Main Authors: Omar Castillo-Aguilera, Patrick Depreux, Ludovic Halby, Paola B. Arimondo, Laurence Goossens
Format: Article
Language:English
Published: MDPI AG 2017-01-01
Series:Biomolecules
Subjects:
DNA methylation
histone methylation
DNMT/HMT crosstalk
DNMT inhibitors
HMT inhibitors
Online Access:http://www.mdpi.com/2218-273X/7/1/3

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