EPILEPSY AND MIGRAINE: NEUROIMAGING AND NEUROPATHOPHYSIOLOGICAL PARALLELS
The aim of this work was to elucidate the structural-metabolic and neuropathophysiological features of epilepsy and migraine, as these diseases share common pathogenetic mechanisms.Materials and methods. Seventy patients with migraine and fifty-six with epilepsy conducted a study using diffusion ten...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
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IRBIS LLC
2016-05-01
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| Series: | Эпилепсия и пароксизмальные состояния |
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| Online Access: | https://www.epilepsia.su/jour/article/view/126 |
| _version_ | 1797879470577680384 |
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| author | V. V. Evstigneev A. N. Michailov O. V. Kistsen K. A. Sadokcha R. A. Sakovich |
| author_facet | V. V. Evstigneev A. N. Michailov O. V. Kistsen K. A. Sadokcha R. A. Sakovich |
| author_sort | V. V. Evstigneev |
| collection | DOAJ |
| description | The aim of this work was to elucidate the structural-metabolic and neuropathophysiological features of epilepsy and migraine, as these diseases share common pathogenetic mechanisms.Materials and methods. Seventy patients with migraine and fifty-six with epilepsy conducted a study using diffusion tensor MRI. Proton spectroscopy performed on 28 patients with epilepsy and 22 with migraine.Results. Data were obtained, indicating changes in fractional anisotropy and average diffusion coefficient and concentration of the main neurometabolites for epilepsy and migraine that characterize the commonality of the pathogenesis of these diseases.Conclusion. The research results allowed to establish the leading role of the hippocampus in the realization paroxysmal states and their pathophysiological basis of the comorbidity. |
| first_indexed | 2024-04-10T02:49:12Z |
| format | Article |
| id | doaj.art-bc719c0ab97d43f78e1827f15bb08518 |
| institution | Directory Open Access Journal |
| issn | 2077-8333 2311-4088 |
| language | Russian |
| last_indexed | 2024-04-10T02:49:12Z |
| publishDate | 2016-05-01 |
| publisher | IRBIS LLC |
| record_format | Article |
| series | Эпилепсия и пароксизмальные состояния |
| spelling | doaj.art-bc719c0ab97d43f78e1827f15bb085182023-03-13T07:44:14ZrusIRBIS LLCЭпилепсия и пароксизмальные состояния2077-83332311-40882016-05-01731825125EPILEPSY AND MIGRAINE: NEUROIMAGING AND NEUROPATHOPHYSIOLOGICAL PARALLELSV. V. Evstigneev0A. N. Michailov1O. V. Kistsen2K. A. Sadokcha3R. A. Sakovich4Belarusian Medical Academy of Postgraduate Education, MinskBelarusian Medical Academy of Postgraduate Education, MinskBelarusian Medical Academy of Postgraduate Education, MinskBelarusian Medical Academy of Postgraduate Education, MinskBelarusian Medical Academy of Postgraduate Education, MinskThe aim of this work was to elucidate the structural-metabolic and neuropathophysiological features of epilepsy and migraine, as these diseases share common pathogenetic mechanisms.Materials and methods. Seventy patients with migraine and fifty-six with epilepsy conducted a study using diffusion tensor MRI. Proton spectroscopy performed on 28 patients with epilepsy and 22 with migraine.Results. Data were obtained, indicating changes in fractional anisotropy and average diffusion coefficient and concentration of the main neurometabolites for epilepsy and migraine that characterize the commonality of the pathogenesis of these diseases.Conclusion. The research results allowed to establish the leading role of the hippocampus in the realization paroxysmal states and their pathophysiological basis of the comorbidity.https://www.epilepsia.su/jour/article/view/126epilepsymigrainediffusion tensor mriproton spectroscopyhippocampus |
| spellingShingle | V. V. Evstigneev A. N. Michailov O. V. Kistsen K. A. Sadokcha R. A. Sakovich EPILEPSY AND MIGRAINE: NEUROIMAGING AND NEUROPATHOPHYSIOLOGICAL PARALLELS Эпилепсия и пароксизмальные состояния epilepsy migraine diffusion tensor mri proton spectroscopy hippocampus |
| title | EPILEPSY AND MIGRAINE: NEUROIMAGING AND NEUROPATHOPHYSIOLOGICAL PARALLELS |
| title_full | EPILEPSY AND MIGRAINE: NEUROIMAGING AND NEUROPATHOPHYSIOLOGICAL PARALLELS |
| title_fullStr | EPILEPSY AND MIGRAINE: NEUROIMAGING AND NEUROPATHOPHYSIOLOGICAL PARALLELS |
| title_full_unstemmed | EPILEPSY AND MIGRAINE: NEUROIMAGING AND NEUROPATHOPHYSIOLOGICAL PARALLELS |
| title_short | EPILEPSY AND MIGRAINE: NEUROIMAGING AND NEUROPATHOPHYSIOLOGICAL PARALLELS |
| title_sort | epilepsy and migraine neuroimaging and neuropathophysiological parallels |
| topic | epilepsy migraine diffusion tensor mri proton spectroscopy hippocampus |
| url | https://www.epilepsia.su/jour/article/view/126 |
| work_keys_str_mv | AT vvevstigneev epilepsyandmigraineneuroimagingandneuropathophysiologicalparallels AT anmichailov epilepsyandmigraineneuroimagingandneuropathophysiologicalparallels AT ovkistsen epilepsyandmigraineneuroimagingandneuropathophysiologicalparallels AT kasadokcha epilepsyandmigraineneuroimagingandneuropathophysiologicalparallels AT rasakovich epilepsyandmigraineneuroimagingandneuropathophysiologicalparallels |