Heparin interferes with the uptake of liposomes in glioma

Heparin interferes with the uptake of liposomes in glioma

In glioblastoma, a malignant primary brain tumor, liposomes have shown promise in pre-clinical and early phase clinical trials as delivery vehicles for therapeutics. However, external factors influencing cellular uptake of liposomes in glioma cells are poorly understood. Heparin and heparin analogue...

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Bibliographic Details
Main Authors: Thomas S. van Solinge, Kristina Pagh Friis, Killian O'Brien, Romy L. Verschoor, Jeroen van Aarle, Arnold Koekman, Xandra O. Breakefield, Pieter Vader, Raymond Schiffelers, Marike Broekman
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:International Journal of Pharmaceutics: X
Subjects:
Liposomes
Heparin
Glioma
Glioblastoma
Uptake
Delivery
Online Access:http://www.sciencedirect.com/science/article/pii/S259015672300035X

Internet

http://www.sciencedirect.com/science/article/pii/S259015672300035X

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