ABT-263 Reduces Hypertrophic Scars by Targeting Apoptosis of Myofibroblasts

Background: Inhibiting proliferation and inducing apoptosis of myofibroblasts is becoming one of the promising and effective ways to treat hypertrophic scar. ABT-263, as an orally bioavailable BCL-2 family inhibitor, has showed great antitumor characteristics by targeting tumor cell apoptosis. The o...

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Main Authors: Xiaolan Yang, Yongqiang Xiao, Chenjian Zhong, Futing Shu, Shichu Xiao, Yongjun Zheng, Zhaofan Xia
פורמט: Article
שפה:English
יצא לאור: Frontiers Media S.A. 2021-01-01
סדרה:Frontiers in Pharmacology
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גישה מקוונת:https://www.frontiersin.org/articles/10.3389/fphar.2020.615505/full