Coronin 1B Controls Endothelial Actin Dynamics at Cell–Cell Junctions and Is Required for Endothelial Network Assembly

Coronin 1B Controls Endothelial Actin Dynamics at Cell–Cell Junctions and Is Required for Endothelial Network Assembly

Development and homeostasis of blood vessels critically depend on the regulation of endothelial cell–cell junctions. VE-cadherin (VEcad)-based cell–cell junctions are connected to the actin cytoskeleton and regulated by actin-binding proteins. Coronin 1B (Coro1B) is an actin binding protein that con...

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Bibliographic Details
Main Authors: Ann-Cathrin Werner, Ludwig T. Weckbach, Melanie Salvermoser, Bettina Pitter, Jiahui Cao, Daniela Maier-Begandt, Ignasi Forné, Hans-Joachim Schnittler, Barbara Walzog, Eloi Montanez
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
endothelial cells
cell–cell junction
actin
tube formation
coronin 1B
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00708/full

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