Non-Coding RNAs: Novel Regulators of Macrophage Homeostasis in Ocular Vascular Diseases
Ocular neovascularization can impair vision and threaten patients’ quality of life. However, the underlying mechanism is far from transparent. In all mammals, macrophages are a population of cells playing pivotal roles in the innate immune system and the first line of defense against pathogens. Ther...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-03-01
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| Series: | Biomolecules |
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| Online Access: | https://www.mdpi.com/2218-273X/14/3/328 |
| _version_ | 1797241888379502592 |
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| author | Qiuyang Zhang Qing Liu Siguo Feng Xiumiao Li Qin Jiang |
| author_facet | Qiuyang Zhang Qing Liu Siguo Feng Xiumiao Li Qin Jiang |
| author_sort | Qiuyang Zhang |
| collection | DOAJ |
| description | Ocular neovascularization can impair vision and threaten patients’ quality of life. However, the underlying mechanism is far from transparent. In all mammals, macrophages are a population of cells playing pivotal roles in the innate immune system and the first line of defense against pathogens. Therefore, it has been speculated that the disfunction of macrophage homeostasis is involved in the development of ocular vascular diseases. Moreover, various studies have found that non-coding RNAs (ncRNAs) regulate macrophage homeostasis. This study reviewed past studies of the regulatory roles of ncRNAs in macrophage homeostasis in ocular vascular diseases. |
| first_indexed | 2024-04-24T18:30:29Z |
| format | Article |
| id | doaj.art-bc7f2d4503d14968b272d72ab13721f9 |
| institution | Directory Open Access Journal |
| issn | 2218-273X |
| language | English |
| last_indexed | 2024-04-24T18:30:29Z |
| publishDate | 2024-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomolecules |
| spelling | doaj.art-bc7f2d4503d14968b272d72ab13721f92024-03-27T13:27:58ZengMDPI AGBiomolecules2218-273X2024-03-0114332810.3390/biom14030328Non-Coding RNAs: Novel Regulators of Macrophage Homeostasis in Ocular Vascular DiseasesQiuyang Zhang0Qing Liu1Siguo Feng2Xiumiao Li3Qin Jiang4Affiliated Eye Hospital, Nanjing Medical University, Nanjing 210029, ChinaAffiliated Eye Hospital, Nanjing Medical University, Nanjing 210029, ChinaAffiliated Eye Hospital, Nanjing Medical University, Nanjing 210029, ChinaAffiliated Eye Hospital, Nanjing Medical University, Nanjing 210029, ChinaAffiliated Eye Hospital, Nanjing Medical University, Nanjing 210029, ChinaOcular neovascularization can impair vision and threaten patients’ quality of life. However, the underlying mechanism is far from transparent. In all mammals, macrophages are a population of cells playing pivotal roles in the innate immune system and the first line of defense against pathogens. Therefore, it has been speculated that the disfunction of macrophage homeostasis is involved in the development of ocular vascular diseases. Moreover, various studies have found that non-coding RNAs (ncRNAs) regulate macrophage homeostasis. This study reviewed past studies of the regulatory roles of ncRNAs in macrophage homeostasis in ocular vascular diseases.https://www.mdpi.com/2218-273X/14/3/328non-coding RNAmacrophagepathological angiogenesis |
| spellingShingle | Qiuyang Zhang Qing Liu Siguo Feng Xiumiao Li Qin Jiang Non-Coding RNAs: Novel Regulators of Macrophage Homeostasis in Ocular Vascular Diseases Biomolecules non-coding RNA macrophage pathological angiogenesis |
| title | Non-Coding RNAs: Novel Regulators of Macrophage Homeostasis in Ocular Vascular Diseases |
| title_full | Non-Coding RNAs: Novel Regulators of Macrophage Homeostasis in Ocular Vascular Diseases |
| title_fullStr | Non-Coding RNAs: Novel Regulators of Macrophage Homeostasis in Ocular Vascular Diseases |
| title_full_unstemmed | Non-Coding RNAs: Novel Regulators of Macrophage Homeostasis in Ocular Vascular Diseases |
| title_short | Non-Coding RNAs: Novel Regulators of Macrophage Homeostasis in Ocular Vascular Diseases |
| title_sort | non coding rnas novel regulators of macrophage homeostasis in ocular vascular diseases |
| topic | non-coding RNA macrophage pathological angiogenesis |
| url | https://www.mdpi.com/2218-273X/14/3/328 |
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