Synthesis of New N-Substituted Phenoxazine Derivatives

This work comprises the synthesis of new phenoxazine derivatives containing N-substituted phenoxazine starting from phenoxazine (1). Synthesis of ethyl acetate phenoxazine (2) through the reaction of phenoxazine with ethylchloroacetate, which reacted with hydrazine hydrate to give 10-aceto hydrazide...

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Main Author: Baghdad Science Journal
Format: Article
Language:Arabic
Published: College of Science for Women, University of Baghdad 2016-06-01
Series:Baghdad Science Journal
Subjects:
Online Access:http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2780
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author Baghdad Science Journal
author_facet Baghdad Science Journal
author_sort Baghdad Science Journal
collection DOAJ
description This work comprises the synthesis of new phenoxazine derivatives containing N-substituted phenoxazine starting from phenoxazine (1). Synthesis of ethyl acetate phenoxazine (2) through the reaction of phenoxazine with ethylchloroacetate, which reacted with hydrazine hydrate to give 10-aceto hydrazide phenoxazine (3), then reacted with formic acid to give 10-[N-formyl acetohydrazide] phenoxazine (4). Reaction of compound (4) with phosphorous pentaoxide or phosphorus pentasulphide to gave 10-[N-methylene-1,3,4-oxadiazole] phenoxazine (5) and 10-[N-methylene-1,3,4-thiadiazole] phenoxazine (6).
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2411-7986
language Arabic
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spelling doaj.art-bc82d324acba4b19b2aefe1d607a95972022-12-21T23:25:43ZaraCollege of Science for Women, University of BaghdadBaghdad Science Journal2078-86652411-79862016-06-0113210.21123/bsj.13.2.360-365Synthesis of New N-Substituted Phenoxazine DerivativesBaghdad Science JournalThis work comprises the synthesis of new phenoxazine derivatives containing N-substituted phenoxazine starting from phenoxazine (1). Synthesis of ethyl acetate phenoxazine (2) through the reaction of phenoxazine with ethylchloroacetate, which reacted with hydrazine hydrate to give 10-aceto hydrazide phenoxazine (3), then reacted with formic acid to give 10-[N-formyl acetohydrazide] phenoxazine (4). Reaction of compound (4) with phosphorous pentaoxide or phosphorus pentasulphide to gave 10-[N-methylene-1,3,4-oxadiazole] phenoxazine (5) and 10-[N-methylene-1,3,4-thiadiazole] phenoxazine (6).http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2780"phenoxazine, ethyl acetate phenoxazine, 10-aceto hydrazide phenoxazine"
spellingShingle Baghdad Science Journal
Synthesis of New N-Substituted Phenoxazine Derivatives
Baghdad Science Journal
"phenoxazine, ethyl acetate phenoxazine, 10-aceto hydrazide phenoxazine"
title Synthesis of New N-Substituted Phenoxazine Derivatives
title_full Synthesis of New N-Substituted Phenoxazine Derivatives
title_fullStr Synthesis of New N-Substituted Phenoxazine Derivatives
title_full_unstemmed Synthesis of New N-Substituted Phenoxazine Derivatives
title_short Synthesis of New N-Substituted Phenoxazine Derivatives
title_sort synthesis of new n substituted phenoxazine derivatives
topic "phenoxazine, ethyl acetate phenoxazine, 10-aceto hydrazide phenoxazine"
url http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2780
work_keys_str_mv AT baghdadsciencejournal synthesisofnewnsubstitutedphenoxazinederivatives