Visual morbidity in thyroid eye disease in Asian Indian patients

Purpose: To describe visual morbidity in thyroid orbitopathy in Asian Indians and the factors influencing its onset. Methods: A retrospective chart review was performed for patients with thyroid related orbitopathy seen between May 2014 and April 2019. Three hundred and one patients were included in...

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Main Authors: Roshmi Gupta, Rwituja Thomas, Fatema Almukhtar, Anjali Kiran
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Indian Journal of Ophthalmology
Subjects:
Online Access:http://www.ijo.in/article.asp?issn=0301-4738;year=2020;volume=68;issue=8;spage=1622;epage=1627;aulast=Gupta
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author Roshmi Gupta
Rwituja Thomas
Fatema Almukhtar
Anjali Kiran
author_facet Roshmi Gupta
Rwituja Thomas
Fatema Almukhtar
Anjali Kiran
author_sort Roshmi Gupta
collection DOAJ
description Purpose: To describe visual morbidity in thyroid orbitopathy in Asian Indians and the factors influencing its onset. Methods: A retrospective chart review was performed for patients with thyroid related orbitopathy seen between May 2014 and April 2019. Three hundred and one patients were included in the study. Relevant history, clinical findings, investigations, and treatment were documented. Results: Nineteen percent of patients had at least 1 visual morbidity feature such as compressive optic neuropathy, exposure keratopathy or diplopia, requiring intravenous glucocorticoid. Male gender, older age, and diabetes were the significant risk factors for high visual morbidity (all P < 0.05). Systemic thyroid status, degree of proptosis, and duration of disease were not significant. Average dose of intravenous glucocorticoid needed was 3.8 g; 24 (7.9%) patients required orbital decompression, and 13 (4.3%) needed eyelid surgery. At the last follow-up, 97% of patients had vision 6/12 or better in both eyes. Conclusion: There is significant visual morbidity found in Indian patients with TED, even with moderate proptosis and systemic control of thyroid status. This is the first set of data on the subject.
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spelling doaj.art-bc881b7ff5bf469aafff62d0e7562e202022-12-22T01:11:37ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892020-01-016881622162710.4103/ijo.IJO_2284_19Visual morbidity in thyroid eye disease in Asian Indian patientsRoshmi GuptaRwituja ThomasFatema AlmukhtarAnjali KiranPurpose: To describe visual morbidity in thyroid orbitopathy in Asian Indians and the factors influencing its onset. Methods: A retrospective chart review was performed for patients with thyroid related orbitopathy seen between May 2014 and April 2019. Three hundred and one patients were included in the study. Relevant history, clinical findings, investigations, and treatment were documented. Results: Nineteen percent of patients had at least 1 visual morbidity feature such as compressive optic neuropathy, exposure keratopathy or diplopia, requiring intravenous glucocorticoid. Male gender, older age, and diabetes were the significant risk factors for high visual morbidity (all P < 0.05). Systemic thyroid status, degree of proptosis, and duration of disease were not significant. Average dose of intravenous glucocorticoid needed was 3.8 g; 24 (7.9%) patients required orbital decompression, and 13 (4.3%) needed eyelid surgery. At the last follow-up, 97% of patients had vision 6/12 or better in both eyes. Conclusion: There is significant visual morbidity found in Indian patients with TED, even with moderate proptosis and systemic control of thyroid status. This is the first set of data on the subject.http://www.ijo.in/article.asp?issn=0301-4738;year=2020;volume=68;issue=8;spage=1622;epage=1627;aulast=Guptadysthyroid optic neuropathyindianthyroid eye disease
spellingShingle Roshmi Gupta
Rwituja Thomas
Fatema Almukhtar
Anjali Kiran
Visual morbidity in thyroid eye disease in Asian Indian patients
Indian Journal of Ophthalmology
dysthyroid optic neuropathy
indian
thyroid eye disease
title Visual morbidity in thyroid eye disease in Asian Indian patients
title_full Visual morbidity in thyroid eye disease in Asian Indian patients
title_fullStr Visual morbidity in thyroid eye disease in Asian Indian patients
title_full_unstemmed Visual morbidity in thyroid eye disease in Asian Indian patients
title_short Visual morbidity in thyroid eye disease in Asian Indian patients
title_sort visual morbidity in thyroid eye disease in asian indian patients
topic dysthyroid optic neuropathy
indian
thyroid eye disease
url http://www.ijo.in/article.asp?issn=0301-4738;year=2020;volume=68;issue=8;spage=1622;epage=1627;aulast=Gupta
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AT rwitujathomas visualmorbidityinthyroideyediseaseinasianindianpatients
AT fatemaalmukhtar visualmorbidityinthyroideyediseaseinasianindianpatients
AT anjalikiran visualmorbidityinthyroideyediseaseinasianindianpatients