A Systematic Way to Infer the Regulation Relations of miRNAs on Target Genes and Critical miRNAs in Cancers

A Systematic Way to Infer the Regulation Relations of miRNAs on Target Genes and Critical miRNAs in Cancers

MicroRNAs (miRNAs) are a class of important non-coding RNAs, which play important roles in tumorigenesis and development by targeting oncogenes or tumor suppressor genes. One miRNA can regulate multiple genes, and one gene can be regulated by multiple miRNAs. To promote the clinical application of m...

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Bibliographic Details
Main Authors: Peng Xu, Qian Wu, Jian Yu, Yongsheng Rao, Zheng Kou, Gang Fang, Xiaolong Shi, Wenbin Liu, Henry Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Genetics
Subjects:
miRNA
influence
cancer
target gene
regulation relation
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00278/full

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