DNA-bridging by an archaeal histone variant via a unique tetramerisation interface
Abstract In eukaryotes, histone paralogues form obligate heterodimers such as H3/H4 and H2A/H2B that assemble into octameric nucleosome particles. Archaeal histones are dimeric and assemble on DNA into ‘hypernucleosome’ particles of varying sizes with each dimer wrapping 30 bp of DNA. These are comp...
Main Authors: | Sapir Ofer, Fabian Blombach, Amanda M. Erkelens, Declan Barker, Zoja Soloviev, Samuel Schwab, Katherine Smollett, Dorota Matelska, Thomas Fouqueau, Nico van der Vis, Nicholas A. Kent, Konstantinos Thalassinos, Remus T. Dame, Finn Werner |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-09-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-023-05348-2 |
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