COVID-19 Delta Variant Co-Infection Mimicking COVID-19 ARDS
The Delta variant of COVID-19 has been associated with severe disease causing a surge in the second half of 2021. Atypical pathogens can be present in those in particular with severe ARDS and can contribute to excess morbidity and mortality. We must maintain a high level of suspicion for these patho...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2022-10-01
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| Series: | Journal of Investigative Medicine High Impact Case Reports |
| Online Access: | https://doi.org/10.1177/23247096221129925 |
| _version_ | 1797996029913595904 |
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| author | James Crosby DO Sarah Semon MD Subramanya Shyam Ganti MD, MBBS Enid Klauber-Choephel MD James Abraham MD |
| author_facet | James Crosby DO Sarah Semon MD Subramanya Shyam Ganti MD, MBBS Enid Klauber-Choephel MD James Abraham MD |
| author_sort | James Crosby DO |
| collection | DOAJ |
| description | The Delta variant of COVID-19 has been associated with severe disease causing a surge in the second half of 2021. Atypical pathogens can be present in those in particular with severe ARDS and can contribute to excess morbidity and mortality. We must maintain a high level of suspicion for these pathogens as this can present an opportunity to dramatically improve the prognosis of a patient with COVID-19 ARDS. However, lend caution to Mycoplasma IgM serology as this can be a false-positive. If suspicion remains high for Mycoplasma pneumoniae infection, sputum polymerase chain reaction (PCR) for M pneumoniae is the gold standard for diagnosis. We present the case of a 42-year-old female with COVID-19 Delta variant presumed ARDS who had co-infection with M pneumoniae confirmed by endotracheal sputum aspirate PCR with rapidly improving oxygenation and extubation within 4 days of effective antibiotic therapy. |
| first_indexed | 2024-04-11T10:09:54Z |
| format | Article |
| id | doaj.art-bc90b3cd7dc044d8be5279a2a6e824f2 |
| institution | Directory Open Access Journal |
| issn | 2324-7096 |
| language | English |
| last_indexed | 2024-04-11T10:09:54Z |
| publishDate | 2022-10-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of Investigative Medicine High Impact Case Reports |
| spelling | doaj.art-bc90b3cd7dc044d8be5279a2a6e824f22022-12-22T04:30:07ZengSAGE PublishingJournal of Investigative Medicine High Impact Case Reports2324-70962022-10-011010.1177/23247096221129925 COVID-19 Delta Variant Co-Infection Mimicking COVID-19 ARDSJames Crosby DO0Sarah Semon MD1Subramanya Shyam Ganti MD, MBBS2Enid Klauber-Choephel MD3James Abraham MD4HCA Healthcare/USF Morsani College of Medicine GME Programs, Tampa, FL, USAHCA Healthcare/USF Morsani College of Medicine GME Programs, Tampa, FL, USAAppalachian Regional Healthcare, Lexington, KY, USAHCA Healthcare/USF Morsani College of Medicine GME Programs, Tampa, FL, USAHCA Healthcare/USF Morsani College of Medicine GME Programs, Tampa, FL, USAThe Delta variant of COVID-19 has been associated with severe disease causing a surge in the second half of 2021. Atypical pathogens can be present in those in particular with severe ARDS and can contribute to excess morbidity and mortality. We must maintain a high level of suspicion for these pathogens as this can present an opportunity to dramatically improve the prognosis of a patient with COVID-19 ARDS. However, lend caution to Mycoplasma IgM serology as this can be a false-positive. If suspicion remains high for Mycoplasma pneumoniae infection, sputum polymerase chain reaction (PCR) for M pneumoniae is the gold standard for diagnosis. We present the case of a 42-year-old female with COVID-19 Delta variant presumed ARDS who had co-infection with M pneumoniae confirmed by endotracheal sputum aspirate PCR with rapidly improving oxygenation and extubation within 4 days of effective antibiotic therapy.https://doi.org/10.1177/23247096221129925 |
| spellingShingle | James Crosby DO Sarah Semon MD Subramanya Shyam Ganti MD, MBBS Enid Klauber-Choephel MD James Abraham MD COVID-19 Delta Variant Co-Infection Mimicking COVID-19 ARDS Journal of Investigative Medicine High Impact Case Reports |
| title | COVID-19 Delta Variant Co-Infection Mimicking COVID-19 ARDS |
| title_full | COVID-19 Delta Variant Co-Infection Mimicking COVID-19 ARDS |
| title_fullStr | COVID-19 Delta Variant Co-Infection Mimicking COVID-19 ARDS |
| title_full_unstemmed | COVID-19 Delta Variant Co-Infection Mimicking COVID-19 ARDS |
| title_short | COVID-19 Delta Variant Co-Infection Mimicking COVID-19 ARDS |
| title_sort | covid 19 delta variant co infection mimicking covid 19 ards |
| url | https://doi.org/10.1177/23247096221129925 |
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