Fluoride and Calcium Release from Alkasite and Glass Ionomer Restorative Dental Materials: In Vitro Study

This study evaluated the effect of pH and temperature on the ion (F<sup>−</sup> and Ca<sup>2+</sup>) release of a resin-based material containing alkaline fillers and a self-setting high-viscous glass ionomer cement. Disks were prepared according to manufacturers’ instruction...

Full description

Bibliographic Details
Main Authors: Alessandro Di Lauro, Fabiana Di Duca, Paolo Montuori, Amanda Maria de Oliveira Dal Piva, João Paulo Mendes Tribst, Alexandre Luiz Souto Borges, Pietro Ausiello
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Journal of Functional Biomaterials
Subjects:
Online Access:https://www.mdpi.com/2079-4983/14/2/109
Description
Summary:This study evaluated the effect of pH and temperature on the ion (F<sup>−</sup> and Ca<sup>2+</sup>) release of a resin-based material containing alkaline fillers and a self-setting high-viscous glass ionomer cement. Disks were prepared according to manufacturers’ instructions for both materials: the EF group (Equia Forte HT filling, GC) and the CN group (<i>Cention N</i>, Ivoclar). Specimens were immersed in 50 mL buffer solution with three different pHs (4.8, 6.8, and 8.8), and stored at 0°, 18°, 37°, and 44 °C. After 24 h, 7 d, and 28 d, cumulative F<sup>−</sup> and Ca<sup>2+</sup> releases were analyzed by chromatography and mass spectrometry, and pH was measured. Both materials showed minimal changes in pH with final values after 28 d of 5.17 ± 0.56 for CN and 5.12 ± 0.24 for EF. In all experimental conditions, the percentages of ion release were higher for EF than for CF. In particular, both materials showed a significant difference in temperature in F<sup>−</sup> release. Regardless of the pH values, the highest Ca<sup>2+</sup> ion release was after 28 days, with a significant difference in temperature for CN and EF. Within the limit of this study, the temperature storage influenced ion release and the high-viscous glass ionomer showed the maximum values.
ISSN:2079-4983