Fluoride and Calcium Release from Alkasite and Glass Ionomer Restorative Dental Materials: In Vitro Study

This study evaluated the effect of pH and temperature on the ion (F<sup>−</sup> and Ca<sup>2+</sup>) release of a resin-based material containing alkaline fillers and a self-setting high-viscous glass ionomer cement. Disks were prepared according to manufacturers’ instruction...

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Main Authors: Alessandro Di Lauro, Fabiana Di Duca, Paolo Montuori, Amanda Maria de Oliveira Dal Piva, João Paulo Mendes Tribst, Alexandre Luiz Souto Borges, Pietro Ausiello
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Journal of Functional Biomaterials
Subjects:
Online Access:https://www.mdpi.com/2079-4983/14/2/109
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author Alessandro Di Lauro
Fabiana Di Duca
Paolo Montuori
Amanda Maria de Oliveira Dal Piva
João Paulo Mendes Tribst
Alexandre Luiz Souto Borges
Pietro Ausiello
author_facet Alessandro Di Lauro
Fabiana Di Duca
Paolo Montuori
Amanda Maria de Oliveira Dal Piva
João Paulo Mendes Tribst
Alexandre Luiz Souto Borges
Pietro Ausiello
author_sort Alessandro Di Lauro
collection DOAJ
description This study evaluated the effect of pH and temperature on the ion (F<sup>−</sup> and Ca<sup>2+</sup>) release of a resin-based material containing alkaline fillers and a self-setting high-viscous glass ionomer cement. Disks were prepared according to manufacturers’ instructions for both materials: the EF group (Equia Forte HT filling, GC) and the CN group (<i>Cention N</i>, Ivoclar). Specimens were immersed in 50 mL buffer solution with three different pHs (4.8, 6.8, and 8.8), and stored at 0°, 18°, 37°, and 44 °C. After 24 h, 7 d, and 28 d, cumulative F<sup>−</sup> and Ca<sup>2+</sup> releases were analyzed by chromatography and mass spectrometry, and pH was measured. Both materials showed minimal changes in pH with final values after 28 d of 5.17 ± 0.56 for CN and 5.12 ± 0.24 for EF. In all experimental conditions, the percentages of ion release were higher for EF than for CF. In particular, both materials showed a significant difference in temperature in F<sup>−</sup> release. Regardless of the pH values, the highest Ca<sup>2+</sup> ion release was after 28 days, with a significant difference in temperature for CN and EF. Within the limit of this study, the temperature storage influenced ion release and the high-viscous glass ionomer showed the maximum values.
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spelling doaj.art-bc90fc7f4a27406b8fdb90714ccb931e2023-11-16T21:24:47ZengMDPI AGJournal of Functional Biomaterials2079-49832023-02-0114210910.3390/jfb14020109Fluoride and Calcium Release from Alkasite and Glass Ionomer Restorative Dental Materials: In Vitro StudyAlessandro Di Lauro0Fabiana Di Duca1Paolo Montuori2Amanda Maria de Oliveira Dal Piva3João Paulo Mendes Tribst4Alexandre Luiz Souto Borges5Pietro Ausiello6Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, Via S. Pansini 5, 80131 Naples, ItalyDepartment of Public Health, University of Naples Federico II, Via Sergio Pansini 5, 80131 Naples, ItalyDepartment of Public Health, University of Naples Federico II, Via Sergio Pansini 5, 80131 Naples, ItalyDepartment of Dental Materials, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, 1081 LA Amsterdam, The NetherlandsDepartment of Oral Regenerative Medicine, Academic Centre for Dentistry Amsterdam (ACTA), Universiteit van Amsterdam and Vrije Universiteit Amsterdam, 1081 LA Amsterdam, The NetherlandsDepartment of Dental Materials and Prosthodontics, Institute of Science and Technology, São Paulo State University (Unesp), São José dos Campos 12245-000, BrazilDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, Via S. Pansini 5, 80131 Naples, ItalyThis study evaluated the effect of pH and temperature on the ion (F<sup>−</sup> and Ca<sup>2+</sup>) release of a resin-based material containing alkaline fillers and a self-setting high-viscous glass ionomer cement. Disks were prepared according to manufacturers’ instructions for both materials: the EF group (Equia Forte HT filling, GC) and the CN group (<i>Cention N</i>, Ivoclar). Specimens were immersed in 50 mL buffer solution with three different pHs (4.8, 6.8, and 8.8), and stored at 0°, 18°, 37°, and 44 °C. After 24 h, 7 d, and 28 d, cumulative F<sup>−</sup> and Ca<sup>2+</sup> releases were analyzed by chromatography and mass spectrometry, and pH was measured. Both materials showed minimal changes in pH with final values after 28 d of 5.17 ± 0.56 for CN and 5.12 ± 0.24 for EF. In all experimental conditions, the percentages of ion release were higher for EF than for CF. In particular, both materials showed a significant difference in temperature in F<sup>−</sup> release. Regardless of the pH values, the highest Ca<sup>2+</sup> ion release was after 28 days, with a significant difference in temperature for CN and EF. Within the limit of this study, the temperature storage influenced ion release and the high-viscous glass ionomer showed the maximum values.https://www.mdpi.com/2079-4983/14/2/109fluoridescalciumionsglass ionomer cementalkasitedental materials
spellingShingle Alessandro Di Lauro
Fabiana Di Duca
Paolo Montuori
Amanda Maria de Oliveira Dal Piva
João Paulo Mendes Tribst
Alexandre Luiz Souto Borges
Pietro Ausiello
Fluoride and Calcium Release from Alkasite and Glass Ionomer Restorative Dental Materials: In Vitro Study
Journal of Functional Biomaterials
fluorides
calcium
ions
glass ionomer cement
alkasite
dental materials
title Fluoride and Calcium Release from Alkasite and Glass Ionomer Restorative Dental Materials: In Vitro Study
title_full Fluoride and Calcium Release from Alkasite and Glass Ionomer Restorative Dental Materials: In Vitro Study
title_fullStr Fluoride and Calcium Release from Alkasite and Glass Ionomer Restorative Dental Materials: In Vitro Study
title_full_unstemmed Fluoride and Calcium Release from Alkasite and Glass Ionomer Restorative Dental Materials: In Vitro Study
title_short Fluoride and Calcium Release from Alkasite and Glass Ionomer Restorative Dental Materials: In Vitro Study
title_sort fluoride and calcium release from alkasite and glass ionomer restorative dental materials in vitro study
topic fluorides
calcium
ions
glass ionomer cement
alkasite
dental materials
url https://www.mdpi.com/2079-4983/14/2/109
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