The anticancer drug tamoxifen is active against Trypanosoma cruzi in vitro but ineffective in the treatment of the acute phase of Chagas disease in mice
The activity of the antineoplastic drug tamoxifen was evaluated against Trypanosoma cruzi. In vitro activity was determined against epimastigote, trypomastigote and amastigote forms of CL14, Y and Y benznidazole resistant T. cruzi strains. Regardless of the strain used, the drug was active against a...
| Main Authors: | , , , , , , |
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| 格式: | 文件 |
| 语言: | English |
| 出版: |
Fundação Oswaldo Cruz (FIOCRUZ)
2010-11-01
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| 丛编: | Memorias do Instituto Oswaldo Cruz |
| 主题: | |
| 在线阅读: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762010000700021 |