Contrasting epigenetic control of transgenes and endogenous genes promotes post-transcriptional transgene silencing in Arabidopsis
Accumulating evidences point to a discrepancy in the epigenetic behaviour of transgenes and endogenous genes. Here, via characterization of mutants impaired in histone demethylases JMJ14 and IBM1, the authors show that transgenes and endogenous genes are regulated by different epigenetic mechanisms...
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-05-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-021-22995-3 |
| _version_ | 1818840859567718400 |
|---|---|
| author | Nicolas Butel Agnès Yu Ivan Le Masson Filipe Borges Taline Elmayan Christelle Taochy Nial R. Gursanscky Jiangling Cao Shengnan Bi Anne Sawyer Bernard J. Carroll Hervé Vaucheret |
| author_facet | Nicolas Butel Agnès Yu Ivan Le Masson Filipe Borges Taline Elmayan Christelle Taochy Nial R. Gursanscky Jiangling Cao Shengnan Bi Anne Sawyer Bernard J. Carroll Hervé Vaucheret |
| author_sort | Nicolas Butel |
| collection | DOAJ |
| description | Accumulating evidences point to a discrepancy in the epigenetic behaviour of transgenes and endogenous genes. Here, via characterization of mutants impaired in histone demethylases JMJ14 and IBM1, the authors show that transgenes and endogenous genes are regulated by different epigenetic mechanisms in Arabidopsis. |
| first_indexed | 2024-12-19T04:16:53Z |
| format | Article |
| id | doaj.art-bc9408c7a12843c8b39d151c7826b1e4 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-19T04:16:53Z |
| publishDate | 2021-05-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-bc9408c7a12843c8b39d151c7826b1e42022-12-21T20:36:16ZengNature PortfolioNature Communications2041-17232021-05-0112111210.1038/s41467-021-22995-3Contrasting epigenetic control of transgenes and endogenous genes promotes post-transcriptional transgene silencing in ArabidopsisNicolas Butel0Agnès Yu1Ivan Le Masson2Filipe Borges3Taline Elmayan4Christelle Taochy5Nial R. Gursanscky6Jiangling Cao7Shengnan Bi8Anne Sawyer9Bernard J. Carroll10Hervé Vaucheret11Institut Jean-Pierre Bourgin, UMR 1318, INRAE, AgroParisTech, Université Paris-SaclayInstitut Jean-Pierre Bourgin, UMR 1318, INRAE, AgroParisTech, Université Paris-SaclayInstitut Jean-Pierre Bourgin, UMR 1318, INRAE, AgroParisTech, Université Paris-SaclayInstitut Jean-Pierre Bourgin, UMR 1318, INRAE, AgroParisTech, Université Paris-SaclayInstitut Jean-Pierre Bourgin, UMR 1318, INRAE, AgroParisTech, Université Paris-SaclayInstitut Jean-Pierre Bourgin, UMR 1318, INRAE, AgroParisTech, Université Paris-SaclaySchool of Chemistry and Molecular Biosciences, The University of QueenslandSchool of Chemistry and Molecular Biosciences, The University of QueenslandSchool of Chemistry and Molecular Biosciences, The University of QueenslandSchool of Chemistry and Molecular Biosciences, The University of QueenslandSchool of Chemistry and Molecular Biosciences, The University of QueenslandInstitut Jean-Pierre Bourgin, UMR 1318, INRAE, AgroParisTech, Université Paris-SaclayAccumulating evidences point to a discrepancy in the epigenetic behaviour of transgenes and endogenous genes. Here, via characterization of mutants impaired in histone demethylases JMJ14 and IBM1, the authors show that transgenes and endogenous genes are regulated by different epigenetic mechanisms in Arabidopsis.https://doi.org/10.1038/s41467-021-22995-3 |
| spellingShingle | Nicolas Butel Agnès Yu Ivan Le Masson Filipe Borges Taline Elmayan Christelle Taochy Nial R. Gursanscky Jiangling Cao Shengnan Bi Anne Sawyer Bernard J. Carroll Hervé Vaucheret Contrasting epigenetic control of transgenes and endogenous genes promotes post-transcriptional transgene silencing in Arabidopsis Nature Communications |
| title | Contrasting epigenetic control of transgenes and endogenous genes promotes post-transcriptional transgene silencing in Arabidopsis |
| title_full | Contrasting epigenetic control of transgenes and endogenous genes promotes post-transcriptional transgene silencing in Arabidopsis |
| title_fullStr | Contrasting epigenetic control of transgenes and endogenous genes promotes post-transcriptional transgene silencing in Arabidopsis |
| title_full_unstemmed | Contrasting epigenetic control of transgenes and endogenous genes promotes post-transcriptional transgene silencing in Arabidopsis |
| title_short | Contrasting epigenetic control of transgenes and endogenous genes promotes post-transcriptional transgene silencing in Arabidopsis |
| title_sort | contrasting epigenetic control of transgenes and endogenous genes promotes post transcriptional transgene silencing in arabidopsis |
| url | https://doi.org/10.1038/s41467-021-22995-3 |
| work_keys_str_mv | AT nicolasbutel contrastingepigeneticcontroloftransgenesandendogenousgenespromotesposttranscriptionaltransgenesilencinginarabidopsis AT agnesyu contrastingepigeneticcontroloftransgenesandendogenousgenespromotesposttranscriptionaltransgenesilencinginarabidopsis AT ivanlemasson contrastingepigeneticcontroloftransgenesandendogenousgenespromotesposttranscriptionaltransgenesilencinginarabidopsis AT filipeborges contrastingepigeneticcontroloftransgenesandendogenousgenespromotesposttranscriptionaltransgenesilencinginarabidopsis AT talineelmayan contrastingepigeneticcontroloftransgenesandendogenousgenespromotesposttranscriptionaltransgenesilencinginarabidopsis AT christelletaochy contrastingepigeneticcontroloftransgenesandendogenousgenespromotesposttranscriptionaltransgenesilencinginarabidopsis AT nialrgursanscky contrastingepigeneticcontroloftransgenesandendogenousgenespromotesposttranscriptionaltransgenesilencinginarabidopsis AT jianglingcao contrastingepigeneticcontroloftransgenesandendogenousgenespromotesposttranscriptionaltransgenesilencinginarabidopsis AT shengnanbi contrastingepigeneticcontroloftransgenesandendogenousgenespromotesposttranscriptionaltransgenesilencinginarabidopsis AT annesawyer contrastingepigeneticcontroloftransgenesandendogenousgenespromotesposttranscriptionaltransgenesilencinginarabidopsis AT bernardjcarroll contrastingepigeneticcontroloftransgenesandendogenousgenespromotesposttranscriptionaltransgenesilencinginarabidopsis AT hervevaucheret contrastingepigeneticcontroloftransgenesandendogenousgenespromotesposttranscriptionaltransgenesilencinginarabidopsis |