Hyperbaric Oxygen in Post-Stroke Patients: A Feasibility Study
Background: Hyperbaric oxygen therapy (HBOT) has been shown to improve the outcomes of certain stroke patients. Our objective was to assess the feasibility of employing HBOT in daily practice in unselected stroke patients with mild-to-moderate residual post-stroke symptoms, considering their ability...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-11-01
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| Series: | Clinical and Translational Neuroscience |
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| Online Access: | https://www.mdpi.com/2514-183X/7/4/41 |
| _version_ | 1797381476159848448 |
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| author | Jörg Schmutz Stefan Engelter Nils Peters Patrick Schmucki Marco Gelsomino |
| author_facet | Jörg Schmutz Stefan Engelter Nils Peters Patrick Schmucki Marco Gelsomino |
| author_sort | Jörg Schmutz |
| collection | DOAJ |
| description | Background: Hyperbaric oxygen therapy (HBOT) has been shown to improve the outcomes of certain stroke patients. Our objective was to assess the feasibility of employing HBOT in daily practice in unselected stroke patients with mild-to-moderate residual post-stroke symptoms, considering their ability to commute our center. Methods: This was an exploratory, interventional, prospective monocentric study on post-stroke patients who have completed their in-hospital stroke rehabilitation. We aimed to include 10 participants who were able to complete 40 daily HBOT sessions (2.0 ATA). Effectiveness was assessed using the National Institutes of Health Stroke Score (NIHSS) pre- and post-HBOT. Results: We recruited 13 patients (12 males) with a mean age of 61 years. Three patients dropped out (two never started HBOT and one withdrew after five sessions because of traveling distance). Post-stroke time was 4–251 months. Among the 10 patients completing the HBOT program, 8 improved their NIHSS by a mean of 1,3 (1–4), while 2 patients’ NIHSS remained unchanged. There were no serious adverse events and no side effects. Conclusions: HBOT was shown to be feasible for mobile post-stroke patients who have completed standard rehabilitation. In the absence of major safety concerns, HBOT seems to be an interesting option post-stroke, with the potential to further improve residual stroke severity. |
| first_indexed | 2024-03-08T20:52:05Z |
| format | Article |
| id | doaj.art-bc94a47bdda0429791ecbaeb8969e674 |
| institution | Directory Open Access Journal |
| issn | 2514-183X |
| language | English |
| last_indexed | 2024-03-08T20:52:05Z |
| publishDate | 2023-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Clinical and Translational Neuroscience |
| spelling | doaj.art-bc94a47bdda0429791ecbaeb8969e6742023-12-22T14:02:16ZengMDPI AGClinical and Translational Neuroscience2514-183X2023-11-01744110.3390/ctn7040041Hyperbaric Oxygen in Post-Stroke Patients: A Feasibility StudyJörg Schmutz0Stefan Engelter1Nils Peters2Patrick Schmucki3Marco Gelsomino4Druckkammerzentrum Basel, Kleinhüningerstrasse 177, 4057 Basel, SwitzerlandNeurology and Neurorehabilitation, University Department of Geriatric Medicine FELIX PLATTER, University of Basel, 4003 Basel, SwitzerlandNeurology and Neurorehabilitation, University Department of Geriatric Medicine FELIX PLATTER, University of Basel, 4003 Basel, SwitzerlandNeurology and Neurorehabilitation, University Department of Geriatric Medicine FELIX PLATTER, University of Basel, 4003 Basel, SwitzerlandDruckkammerzentrum Basel, Kleinhüningerstrasse 177, 4057 Basel, SwitzerlandBackground: Hyperbaric oxygen therapy (HBOT) has been shown to improve the outcomes of certain stroke patients. Our objective was to assess the feasibility of employing HBOT in daily practice in unselected stroke patients with mild-to-moderate residual post-stroke symptoms, considering their ability to commute our center. Methods: This was an exploratory, interventional, prospective monocentric study on post-stroke patients who have completed their in-hospital stroke rehabilitation. We aimed to include 10 participants who were able to complete 40 daily HBOT sessions (2.0 ATA). Effectiveness was assessed using the National Institutes of Health Stroke Score (NIHSS) pre- and post-HBOT. Results: We recruited 13 patients (12 males) with a mean age of 61 years. Three patients dropped out (two never started HBOT and one withdrew after five sessions because of traveling distance). Post-stroke time was 4–251 months. Among the 10 patients completing the HBOT program, 8 improved their NIHSS by a mean of 1,3 (1–4), while 2 patients’ NIHSS remained unchanged. There were no serious adverse events and no side effects. Conclusions: HBOT was shown to be feasible for mobile post-stroke patients who have completed standard rehabilitation. In the absence of major safety concerns, HBOT seems to be an interesting option post-stroke, with the potential to further improve residual stroke severity.https://www.mdpi.com/2514-183X/7/4/41post-strokehyperbaric oxygen therapyfeasibilityoutpatient |
| spellingShingle | Jörg Schmutz Stefan Engelter Nils Peters Patrick Schmucki Marco Gelsomino Hyperbaric Oxygen in Post-Stroke Patients: A Feasibility Study Clinical and Translational Neuroscience post-stroke hyperbaric oxygen therapy feasibility outpatient |
| title | Hyperbaric Oxygen in Post-Stroke Patients: A Feasibility Study |
| title_full | Hyperbaric Oxygen in Post-Stroke Patients: A Feasibility Study |
| title_fullStr | Hyperbaric Oxygen in Post-Stroke Patients: A Feasibility Study |
| title_full_unstemmed | Hyperbaric Oxygen in Post-Stroke Patients: A Feasibility Study |
| title_short | Hyperbaric Oxygen in Post-Stroke Patients: A Feasibility Study |
| title_sort | hyperbaric oxygen in post stroke patients a feasibility study |
| topic | post-stroke hyperbaric oxygen therapy feasibility outpatient |
| url | https://www.mdpi.com/2514-183X/7/4/41 |
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