Primary invasive squamous cell carcinoma of the nipple in an adult male: A case report and brief review of literature

This is a case report of a rare and uncommon primary invasive squamous cell carcinoma (SCC) of the nipple in a male patient. The patient presented with an ulcerated growth over the left nipple for the last 20 years, which progressed over the last 6 months. He underwent wide local excision with level...

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Main Authors: Priyansh Jain, Prapti Acharya, Mahesh Sultania, Dillip K Muduly, Mukund N Sable
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-01-01
Series:Indian Journal of Pathology and Microbiology
Subjects:
Online Access:http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2024;volume=67;issue=1;spage=145;epage=148;aulast=Jain
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author Priyansh Jain
Prapti Acharya
Mahesh Sultania
Dillip K Muduly
Mukund N Sable
author_facet Priyansh Jain
Prapti Acharya
Mahesh Sultania
Dillip K Muduly
Mukund N Sable
author_sort Priyansh Jain
collection DOAJ
description This is a case report of a rare and uncommon primary invasive squamous cell carcinoma (SCC) of the nipple in a male patient. The patient presented with an ulcerated growth over the left nipple for the last 20 years, which progressed over the last 6 months. He underwent wide local excision with level II axillary lymph node dissection, and one out of 42 lymph nodes harvested showed metastatic deposit. The patient was planned for follow-up with no adjuvant treatment, and had no evidence of local-regional or distant recurrence at 24 months follow-up. The primary invasive SCC of male nipple is very rare, and its diagnosis is challenging as it can be confused with other clinical conditions. However, a histopathological examination with immunohistochemistry can differentiate primary SCC nipple from other differential diagnoses. The treatment options for cutaneous SCC include surgical excision, cryotherapy, electrosurgery, topical ointments, definitive radiation therapy, and photodynamic therapy. Regional lymph node dissection in SCC nipple could potentially have therapeutic and prognostic significance.
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spelling doaj.art-bc94e1a3d5e143dd96b9792520d914a72024-04-13T03:00:14ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49290974-51302024-01-0167114514810.4103/ijpm.ijpm_445_23Primary invasive squamous cell carcinoma of the nipple in an adult male: A case report and brief review of literaturePriyansh JainPrapti AcharyaMahesh SultaniaDillip K MudulyMukund N SableThis is a case report of a rare and uncommon primary invasive squamous cell carcinoma (SCC) of the nipple in a male patient. The patient presented with an ulcerated growth over the left nipple for the last 20 years, which progressed over the last 6 months. He underwent wide local excision with level II axillary lymph node dissection, and one out of 42 lymph nodes harvested showed metastatic deposit. The patient was planned for follow-up with no adjuvant treatment, and had no evidence of local-regional or distant recurrence at 24 months follow-up. The primary invasive SCC of male nipple is very rare, and its diagnosis is challenging as it can be confused with other clinical conditions. However, a histopathological examination with immunohistochemistry can differentiate primary SCC nipple from other differential diagnoses. The treatment options for cutaneous SCC include surgical excision, cryotherapy, electrosurgery, topical ointments, definitive radiation therapy, and photodynamic therapy. Regional lymph node dissection in SCC nipple could potentially have therapeutic and prognostic significance.http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2024;volume=67;issue=1;spage=145;epage=148;aulast=Jaincase reportmalenipplereview of literaturesquamous cell carcinoma
spellingShingle Priyansh Jain
Prapti Acharya
Mahesh Sultania
Dillip K Muduly
Mukund N Sable
Primary invasive squamous cell carcinoma of the nipple in an adult male: A case report and brief review of literature
Indian Journal of Pathology and Microbiology
case report
male
nipple
review of literature
squamous cell carcinoma
title Primary invasive squamous cell carcinoma of the nipple in an adult male: A case report and brief review of literature
title_full Primary invasive squamous cell carcinoma of the nipple in an adult male: A case report and brief review of literature
title_fullStr Primary invasive squamous cell carcinoma of the nipple in an adult male: A case report and brief review of literature
title_full_unstemmed Primary invasive squamous cell carcinoma of the nipple in an adult male: A case report and brief review of literature
title_short Primary invasive squamous cell carcinoma of the nipple in an adult male: A case report and brief review of literature
title_sort primary invasive squamous cell carcinoma of the nipple in an adult male a case report and brief review of literature
topic case report
male
nipple
review of literature
squamous cell carcinoma
url http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2024;volume=67;issue=1;spage=145;epage=148;aulast=Jain
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AT praptiacharya primaryinvasivesquamouscellcarcinomaofthenippleinanadultmaleacasereportandbriefreviewofliterature
AT maheshsultania primaryinvasivesquamouscellcarcinomaofthenippleinanadultmaleacasereportandbriefreviewofliterature
AT dillipkmuduly primaryinvasivesquamouscellcarcinomaofthenippleinanadultmaleacasereportandbriefreviewofliterature
AT mukundnsable primaryinvasivesquamouscellcarcinomaofthenippleinanadultmaleacasereportandbriefreviewofliterature