NEW EXPERIMENTAL PATHOGENETICALLY GROUNDED VARICOCELE MODE
Aim. The main aim of the study was to develop a pathogenetically grounded varicocele model and to compare it with the well-known one.Materials and methods. 30 male mongrel laboratory rats were divided in 3 equal groups, in the 1st group Saypol technique was performed, in the 2nd – one-time partial l...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Ministry of Healthcare of the Russian Federation. “Kuban State Medical University”
2018-05-01
|
| Series: | Кубанский научный медицинский вестник |
| Subjects: | |
| Online Access: | https://ksma.elpub.ru/jour/article/view/1128 |
| _version_ | 1797295496563261440 |
|---|---|
| author | M. A. Berdnikov N. V. Antipov Yu. K. Gulkov |
| author_facet | M. A. Berdnikov N. V. Antipov Yu. K. Gulkov |
| author_sort | M. A. Berdnikov |
| collection | DOAJ |
| description | Aim. The main aim of the study was to develop a pathogenetically grounded varicocele model and to compare it with the well-known one.Materials and methods. 30 male mongrel laboratory rats were divided in 3 equal groups, in the 1st group Saypol technique was performed, in the 2nd – one-time partial ligation of both spermatic cords with following testicles abdominisation. The 3rd group was the control one. There was a gonadectomy with following histological investigation on the 7th, 15th and 30th days. Results. Group 1 was presented with adhesions in abdominal cavity and hydronephrosis in all rats. The changes in the spermatic veins and testicles were reached both in the 1st and 2nd groups with more signifi ones in the 2nd group by the 15th day. There were phlebectasia, tunica media thinning, infl infi of the testicles with spermatogenous epithelium and mature germ cells necrobiosis, in some cases also arterial vessels proliferation and even spermatogenesis recovery.Conclusion. Thereby, the use of the suggested technique is more grounded from the technical, economical and pathogenetic points of view. |
| first_indexed | 2024-03-07T21:48:49Z |
| format | Article |
| id | doaj.art-bc95120b0c574dd8a4aaf99fa090e80b |
| institution | Directory Open Access Journal |
| issn | 1608-6228 2541-9544 |
| language | Russian |
| last_indexed | 2024-03-07T21:48:49Z |
| publishDate | 2018-05-01 |
| publisher | Ministry of Healthcare of the Russian Federation. “Kuban State Medical University” |
| record_format | Article |
| series | Кубанский научный медицинский вестник |
| spelling | doaj.art-bc95120b0c574dd8a4aaf99fa090e80b2024-02-25T10:57:22ZrusMinistry of Healthcare of the Russian Federation. “Kuban State Medical University”Кубанский научный медицинский вестник1608-62282541-95442018-05-01252404410.25207/1608-6228-2018-25-2-40-44919NEW EXPERIMENTAL PATHOGENETICALLY GROUNDED VARICOCELE MODEM. A. Berdnikov0N. V. Antipov1Yu. K. Gulkov2State Educational Organisation of Higher Professional Education M. Gorky Donetsk National Medical University of the Ministry of Healthcare of the Donetsk People’s RepublicState Educational Organisation of Higher Professional Education M. Gorky Donetsk National Medical University of the Ministry of Healthcare of the Donetsk People’s RepublicDonetsk Clinical Community-based Medical Organisation of the Ministry of Healthcare of the Donetsk People’sRepublicAim. The main aim of the study was to develop a pathogenetically grounded varicocele model and to compare it with the well-known one.Materials and methods. 30 male mongrel laboratory rats were divided in 3 equal groups, in the 1st group Saypol technique was performed, in the 2nd – one-time partial ligation of both spermatic cords with following testicles abdominisation. The 3rd group was the control one. There was a gonadectomy with following histological investigation on the 7th, 15th and 30th days. Results. Group 1 was presented with adhesions in abdominal cavity and hydronephrosis in all rats. The changes in the spermatic veins and testicles were reached both in the 1st and 2nd groups with more signifi ones in the 2nd group by the 15th day. There were phlebectasia, tunica media thinning, infl infi of the testicles with spermatogenous epithelium and mature germ cells necrobiosis, in some cases also arterial vessels proliferation and even spermatogenesis recovery.Conclusion. Thereby, the use of the suggested technique is more grounded from the technical, economical and pathogenetic points of view.https://ksma.elpub.ru/jour/article/view/1128varicocelemodelinglaboratory ratsspermatogenesis |
| spellingShingle | M. A. Berdnikov N. V. Antipov Yu. K. Gulkov NEW EXPERIMENTAL PATHOGENETICALLY GROUNDED VARICOCELE MODE Кубанский научный медицинский вестник varicocele modeling laboratory rats spermatogenesis |
| title | NEW EXPERIMENTAL PATHOGENETICALLY GROUNDED VARICOCELE MODE |
| title_full | NEW EXPERIMENTAL PATHOGENETICALLY GROUNDED VARICOCELE MODE |
| title_fullStr | NEW EXPERIMENTAL PATHOGENETICALLY GROUNDED VARICOCELE MODE |
| title_full_unstemmed | NEW EXPERIMENTAL PATHOGENETICALLY GROUNDED VARICOCELE MODE |
| title_short | NEW EXPERIMENTAL PATHOGENETICALLY GROUNDED VARICOCELE MODE |
| title_sort | new experimental pathogenetically grounded varicocele mode |
| topic | varicocele modeling laboratory rats spermatogenesis |
| url | https://ksma.elpub.ru/jour/article/view/1128 |
| work_keys_str_mv | AT maberdnikov newexperimentalpathogeneticallygroundedvaricocelemode AT nvantipov newexperimentalpathogeneticallygroundedvaricocelemode AT yukgulkov newexperimentalpathogeneticallygroundedvaricocelemode |