Evoked compound action potential (ECAP)-controlled closed-loop spinal cord stimulation in an experimental model of neuropathic pain in rats

Evoked compound action potential (ECAP)-controlled closed-loop spinal cord stimulation in an experimental model of neuropathic pain in rats

Abstract Background Preclinical models of spinal cord stimulation (SCS) are lacking objective measurements to inform translationally applicable SCS parameters. The evoked compound action potential (ECAP) represents a measure of dorsal column fiber activation. This measure approximates the onset of S...

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Bibliographic Details
Main Authors: Eline M. Versantvoort, Birte E. Dietz, Dave Mugan, Quoc C. Vuong, Saimir Luli, Ilona Obara
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Bioelectronic Medicine
Subjects:
Evoked compound action potential
Rat
Closed-loop
Spinal cord stimulation
Neuropathic pain
In vivo electrophysiology
Online Access:https://doi.org/10.1186/s42234-023-00134-1

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