Comparing the 30-Day Mortality for Hip Fractures in Patients with and without COVID-19: An Updated Meta-Analysis

We conducted an updated meta-analysis to evaluate the 30-day mortality of hip fractures during the COVID-19 pandemic and assess mortality rates by country. We systematically searched Medline, EMBASE, and the Cochrane Library up to November 2022 for studies on the 30-day mortality of hip fractures du...

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Main Authors: Sojune Hwang, Chiwon Ahn, Moonho Won
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Journal of Personalized Medicine
Subjects:
Online Access:https://www.mdpi.com/2075-4426/13/4/669
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author Sojune Hwang
Chiwon Ahn
Moonho Won
author_facet Sojune Hwang
Chiwon Ahn
Moonho Won
author_sort Sojune Hwang
collection DOAJ
description We conducted an updated meta-analysis to evaluate the 30-day mortality of hip fractures during the COVID-19 pandemic and assess mortality rates by country. We systematically searched Medline, EMBASE, and the Cochrane Library up to November 2022 for studies on the 30-day mortality of hip fractures during the pandemic. Two reviewers used the Newcastle–Ottawa tool to independently assess the methodological quality of the included studies. We conducted a meta-analysis and systematic review including 40 eligible studies with 17,753 patients with hip fractures, including 2280 patients with COVID-19 (12.8%). The overall 30-day mortality rate for hip fractures during the pandemic was 12.6% from published studies. The 30-day mortality of patients with hip fractures who had COVID-19 was significantly higher than those without COVID-19 (OR, 7.10; 95% CI, 5.51–9.15; I<sup>2</sup> = 57%). The hip fracture mortality rate increased during the pandemic and varied by country, with the highest rates found in Europe, particularly the United Kingdom (UK) and Spain. COVID-19 may have contributed to the increased 30-day mortality rate in hip fracture patients. The mortality rate of hip fracture in patients without COVID-19 did not change during the pandemic.
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spelling doaj.art-bc97e3ceb8e045788e3df4b4d69c43cb2023-11-17T20:00:28ZengMDPI AGJournal of Personalized Medicine2075-44262023-04-0113466910.3390/jpm13040669Comparing the 30-Day Mortality for Hip Fractures in Patients with and without COVID-19: An Updated Meta-AnalysisSojune Hwang0Chiwon Ahn1Moonho Won2Department of Emergency Medicine, College of Medicine, Chung-Ang University, Seoul 06974, Republic of KoreaDepartment of Emergency Medicine, College of Medicine, Chung-Ang University, Seoul 06974, Republic of KoreaDepartment of Emergency Medicine, College of Medicine, Chung-Ang University, Seoul 06974, Republic of KoreaWe conducted an updated meta-analysis to evaluate the 30-day mortality of hip fractures during the COVID-19 pandemic and assess mortality rates by country. We systematically searched Medline, EMBASE, and the Cochrane Library up to November 2022 for studies on the 30-day mortality of hip fractures during the pandemic. Two reviewers used the Newcastle–Ottawa tool to independently assess the methodological quality of the included studies. We conducted a meta-analysis and systematic review including 40 eligible studies with 17,753 patients with hip fractures, including 2280 patients with COVID-19 (12.8%). The overall 30-day mortality rate for hip fractures during the pandemic was 12.6% from published studies. The 30-day mortality of patients with hip fractures who had COVID-19 was significantly higher than those without COVID-19 (OR, 7.10; 95% CI, 5.51–9.15; I<sup>2</sup> = 57%). The hip fracture mortality rate increased during the pandemic and varied by country, with the highest rates found in Europe, particularly the United Kingdom (UK) and Spain. COVID-19 may have contributed to the increased 30-day mortality rate in hip fracture patients. The mortality rate of hip fracture in patients without COVID-19 did not change during the pandemic.https://www.mdpi.com/2075-4426/13/4/669hip fractureCOVID-19pandemicmortality
spellingShingle Sojune Hwang
Chiwon Ahn
Moonho Won
Comparing the 30-Day Mortality for Hip Fractures in Patients with and without COVID-19: An Updated Meta-Analysis
Journal of Personalized Medicine
hip fracture
COVID-19
pandemic
mortality
title Comparing the 30-Day Mortality for Hip Fractures in Patients with and without COVID-19: An Updated Meta-Analysis
title_full Comparing the 30-Day Mortality for Hip Fractures in Patients with and without COVID-19: An Updated Meta-Analysis
title_fullStr Comparing the 30-Day Mortality for Hip Fractures in Patients with and without COVID-19: An Updated Meta-Analysis
title_full_unstemmed Comparing the 30-Day Mortality for Hip Fractures in Patients with and without COVID-19: An Updated Meta-Analysis
title_short Comparing the 30-Day Mortality for Hip Fractures in Patients with and without COVID-19: An Updated Meta-Analysis
title_sort comparing the 30 day mortality for hip fractures in patients with and without covid 19 an updated meta analysis
topic hip fracture
COVID-19
pandemic
mortality
url https://www.mdpi.com/2075-4426/13/4/669
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AT chiwonahn comparingthe30daymortalityforhipfracturesinpatientswithandwithoutcovid19anupdatedmetaanalysis
AT moonhowon comparingthe30daymortalityforhipfracturesinpatientswithandwithoutcovid19anupdatedmetaanalysis