2D-Quantitative structure activity relationship (QSAR) modeling, docking studies, synthesis and in-vitro evaluation of 1,3,4-thiadiazole tethered coumarin derivatives as antiproliferative agents

2D-Quantitative structure activity relationship (QSAR) modeling, docking studies, synthesis and in-vitro evaluation of 1,3,4-thiadiazole tethered coumarin derivatives as antiproliferative agents

Cancer is one of the leading causes of deaths globally. Despite many anticancer agents in the market, cancer stood as a major health concern to humanity due to the problems like drug resistance, toxicities and economic burden etc., and these issues strongly impose the scientists for the development...

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Bibliographic Details
Main Authors: Natarajan Ramalakshmi, Pasumalai Manimegalai, Richie R. Bhandare, Subramani Arun Kumar, Afzal B. Shaik
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Journal of Saudi Chemical Society
Subjects:
QSAR
Antiproliferative
Thiadiazole
Coumarin
Docking
Regression
Online Access:http://www.sciencedirect.com/science/article/pii/S1319610321000843

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