Three New Oleanane-Type Triterpenoidal Glycosides from <i>Impatiens balsamina</i> and Their Biological Activity

Three new oleanane-type triterpenoidal glycosides, imbalosides A–C (<b>1</b>–<b>3</b>), were isolated from the white flowers of <i>Impatiens balsamina</i>. The structures of these phytochemical constituents (<b>1</b>–<b>3</b>) were elucidat...

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Bibliographic Details
Main Authors: Tae Hyun Lee, Won Se Suh, Lalita Subedi, Sun Yeou Kim, Sang Un Choi, Kang Ro Lee, Chung Sub Kim
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Plants
Subjects:
Online Access:https://www.mdpi.com/2223-7747/9/9/1083
Description
Summary:Three new oleanane-type triterpenoidal glycosides, imbalosides A–C (<b>1</b>–<b>3</b>), were isolated from the white flowers of <i>Impatiens balsamina</i>. The structures of these phytochemical constituents (<b>1</b>–<b>3</b>) were elucidated through 1D and 2D Nuclear Magnetic Resonance (NMR) and Mass Spectrometry (MS) data analyses followed by chemical methods. All the characterized compounds (<b>1</b>–<b>3</b>) were evaluated for their antiproliferative activity against four human tumor cell lines (A549, SK-OV-3, SK-MEL-2, and BT549) and their anti-neuroinflammatory activity on the basis of inhibition levels of nitric oxide (NO) in the lipopolysaccharide (LPS)-stimulated murine microglia BV-2 cell lines.
ISSN:2223-7747