Systems crosstalk between antiviral response and cancerous pathways via extracellular vesicles in HIV-1-associated colorectal cancer

Systems crosstalk between antiviral response and cancerous pathways via extracellular vesicles in HIV-1-associated colorectal cancer

HIV-1 associated colorectal cancer (HA-CRC) is one of the most understudied non-AIDS-defining cancers. In this study, we analyzed the proteome of HA-CRC and the paired remote tissues (HA-RT) through data-independent acquisition mass spectrometry (MS). The quantified proteins could differentiate the...

Full description

Bibliographic Details
Main Authors:	Zimei Chen, Ke Yang, Jiayi Zhang, Shufan Ren, Hui Chen, Jiahui Guo, Yizhi Cui, Tong Wang, Min Wang
Format:	Article
Language:	English
Published:	Elsevier 2023-01-01
Series:	Computational and Structural Biotechnology Journal
Subjects:	HIV-1-associated colorectal cancer Proteomics HIV-1 reservoir Extracellular vesicles IFN pathway Cell-associated HIV-1 RNA
Online Access:	http://www.sciencedirect.com/science/article/pii/S2001037023002234

Similar Items

An Omics Approach to Extracellular Vesicles from HIV-1 Infected Cells
by: Robert A. Barclay, et al.
Published: (2019-07-01)

Extracellular Vesicles in Smoking-Mediated HIV Pathogenesis and their Potential Role in Biomarker Discovery and Therapeutic Interventions
by: Sanjana Haque, et al.
Published: (2020-04-01)

HIV‐1 Nef is carried on the surface of extracellular vesicles
by: Christophe Vanpouille, et al.
Published: (2024-07-01)

Extracellular Vesicles from Infected Cells Are Released Prior to Virion Release
by: Yuriy Kim, et al.
Published: (2021-04-01)

Cocaine augments neuro-inflammation via modulating extracellular vesicle release in HIV-1 infected immune cells
by: Manojkumar Narayanan, et al.
Published: (2021-09-01)

Proteomic analysis of cerebrospinal fluid extracellular vesicles reveals synaptic injury, inflammation, and stress response markers in HIV patients with cognitive impairment
by: Debjani Guha, et al.
Published: (2019-12-01)

Extracellular vesicles produced by HIV-1 Nef-expressing cells induce myelin impairment and oligodendrocyte damage in the mouse central nervous system
by: Jessica K. Schenck, et al.
Published: (2024-05-01)

Glutaminase 1 regulates the release of extracellular vesicles during neuroinflammation through key metabolic intermediate alpha-ketoglutarate
by: Beiqing Wu, et al.
Published: (2018-03-01)

Autophagy Deregulation in HIV-1-Infected Cells Increases Extracellular Vesicle Release and Contributes to TLR3 Activation
by: Catherine DeMarino, et al.
Published: (2024-04-01)

HIV-1 Nef Protein Affects Cytokine and Extracellular Vesicles Production in the GEN2.2 Plasmacytoid Dendritic Cell Line
by: Alessandra Aiello, et al.
Published: (2021-12-01)

Neuronal-derived extracellular vesicles are enriched in the brain and serum of HIV-1 transgenic rats
by: Raghubendra Singh Dagur, et al.
Published: (2020-01-01)

Extracellular vesicles and chronic inflammation during HIV infection
by: Paula Soledad Pérez, et al.
Published: (2019-12-01)

The extracellular vesicles in HIV infection and progression: mechanisms, and theranostic implications
by: Zhen Tang, et al.
Published: (2024-04-01)

miRNA profiling of primate cervicovaginal lavage and extracellular vesicles reveals miR‐186‐5p as a potential antiretroviral factor in macrophages
by: Zezhou Zhao, et al.
Published: (2020-10-01)

Immune Cells Release MicroRNA-155 Enriched Extracellular Vesicles That Promote HIV-1 Infection
by: Julien Boucher, et al.
Published: (2023-01-01)

The Landscape of IFN/ISG Signaling in HIV-1-Infected Macrophages and Its Possible Role in the HIV-1 Latency
by: Masyelly Rojas, et al.
Published: (2021-09-01)

Editorial: The relevance of molecular mechanisms in HIV-1 latency and reactivation from latency
by: Alexander O. Pasternak, et al.
Published: (2023-04-01)

Corrigendum: Editorial: The relevance of molecular mechanisms in HIV-1 latency and reactivation from latency
by: Alexander O. Pasternak, et al.
Published: (2023-05-01)

Electrostatic Surface Properties of Blood and Semen Extracellular Vesicles: Implications of Sialylation and HIV-Induced Changes on EV Internalization
by: Hussein Kaddour, et al.
Published: (2020-10-01)

Hiding in plain sight – platelets, the silent carriers of HIV-1
by: Yvonne Baumer, et al.
Published: (2021-11-01)

Neutral sphingomyelinase 2 inhibition attenuates extracellular vesicle release and improves neurobehavioral deficits in murine HIV
by: Xiaolei Zhu, et al.
Published: (2022-07-01)

Persistent HIV-1 transcription in CD4+ T cells from ART-suppressed individuals can originate from biologically competent proviruses
by: M. Vignoles, et al.
Published: (2021-09-01)

Repurposing Antiviral Protease Inhibitors Using Extracellular Vesicles for Potential Therapy of COVID-19
by: Santosh Kumar, et al.
Published: (2020-04-01)

Second European Round Table on the Future Management of HIV
by: Casper Rokx, et al.
Published: (2015-07-01)

The versatile role of exosomes in human retroviral infections: from immunopathogenesis to clinical application
by: Jafar Rezaie, et al.
Published: (2021-01-01)

Impact of Analytical Treatment Interruption on Burden and Diversification of HIV Peripheral Reservoir: A Pilot Study
by: Rossana Scutari, et al.
Published: (2021-07-01)

Interactions of Monocytes, HIV, and ART Identified by an Innovative scRNAseq Pipeline: Pathways to Reservoirs and HIV-Associated Comorbidities
by: Rosiris León-Rivera, et al.
Published: (2020-08-01)

Extracellular Vesicles in the Pathogenesis of Viral Infections in Humans
by: Allen Caobi, et al.
Published: (2020-10-01)

Measuring replication competent HIV-1: advances and challenges in defining the latent reservoir
by: Zheng Wang, et al.
Published: (2018-02-01)

Are HIV-1-Specific Antibody Levels Potentially Useful Laboratory Markers to Estimate HIV Reservoir Size? A Review
by: Silvere D. Zaongo, et al.
Published: (2021-11-01)

IRF7 and RNH1 are modifying factors of HIV-1 reservoirs: a genome-wide association analysis
by: Zhenhua Zhang, et al.
Published: (2021-11-01)

Factors associated with unquantifiable total HIV-1 DNA in peripheral blood in persons living with HIV: An observational study
by: Aurélie Ram, et al.
Published: (2024-03-01)

Epigenetic Mechanisms of HIV-1 Persistence
by: Roxane Verdikt, et al.
Published: (2021-05-01)

The Role of Extracellular Vesicles as Allies of HIV, HCV and SARS Viruses
by: Flavia Giannessi, et al.
Published: (2020-05-01)

The Splice of Life: Does RNA Processing Have a Role in HIV-1 Persistence?
by: Alexander O. Pasternak, et al.
Published: (2021-09-01)

Immunotherapy in People With HIV and Cancer
by: Camille E. Puronen, et al.
Published: (2019-08-01)

Magnetoelectric Extracellular Vesicle Latency-Targeting (MELT) Nanotherapeutic for the Block-Lock-and-Kill HIV Eradication Strategy
by: Mickensone Andre, et al.
Published: (2025-01-01)

Extracellular vesicles regulate gap junction-mediated intercellular communication and HIV-1 infection of human neural progenitor cells
by: Hyung Joon Cho, et al.
Published: (2021-07-01)

Effect of Kinases in Extracellular Vesicles from HIV-1-Infected Cells on Bystander Cells
by: Gifty A. Mensah, et al.
Published: (2025-01-01)

Methamphetamine Induces the Release of Proadhesive Extracellular Vesicles and Promotes Syncytia Formation: A Potential Role in HIV-1 Neuropathogenesis
by: Subhash Chand, et al.
Published: (2022-03-01)