A Century of Vitamin E: Early Milestones and Future Directions in Animal Nutrition
Vitamin E, consisting of four tocopherols and four tocotrienols, with α-tocopherol as the most biologically active form, has a significant history in scientific research. It was first identified in the 1920s for its role in preventing neonatal mortality in rats. Over time, its chemical structure was...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-07-01
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| Series: | Agriculture |
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| Online Access: | https://www.mdpi.com/2077-0472/13/8/1526 |
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| author | Yauheni Shastak Ute Obermueller-Jevic Wolf Pelletier |
| author_facet | Yauheni Shastak Ute Obermueller-Jevic Wolf Pelletier |
| author_sort | Yauheni Shastak |
| collection | DOAJ |
| description | Vitamin E, consisting of four tocopherols and four tocotrienols, with α-tocopherol as the most biologically active form, has a significant history in scientific research. It was first identified in the 1920s for its role in preventing neonatal mortality in rats. Over time, its chemical structure was elucidated, and its importance in the immune system, skin health, anti-inflammatory properties, and hormonal balance was revealed. Vitamin E production has evolved from natural sourcing to efficient synthesis with standardized potency units. Initially, animal studies focused on reproductive health and growth disorders, but later research highlighted vitamin E’s role in preventing encephalomalacia in domestic fowl and muscular dystrophy in various animals. Today, vitamin E is commonly used as a feed additive to enhance animal health and immune function. Despite substantial knowledge about its role in animal nutrition, several questions remain unanswered. Current research seeks to determine optimal supplementation levels, interactions with other nutrients, impacts on gene expression, cell signaling, and communication, as well as the effects of high dosages in livestock. Vitamin E continues to be a crucial component in improving animal health, and ongoing research aims to uncover its benefits and mechanisms of action further. |
| first_indexed | 2024-03-11T00:12:51Z |
| format | Article |
| id | doaj.art-bc9e4928bcd2446dacf16a9cb9f86214 |
| institution | Directory Open Access Journal |
| issn | 2077-0472 |
| language | English |
| last_indexed | 2024-03-11T00:12:51Z |
| publishDate | 2023-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Agriculture |
| spelling | doaj.art-bc9e4928bcd2446dacf16a9cb9f862142023-11-18T23:51:20ZengMDPI AGAgriculture2077-04722023-07-01138152610.3390/agriculture13081526A Century of Vitamin E: Early Milestones and Future Directions in Animal NutritionYauheni Shastak0Ute Obermueller-Jevic1Wolf Pelletier2Nutrition & Health Division, BASF SE, 67063 Ludwigshafen am Rhein, GermanyNutrition & Health Division, BASF SE, 67063 Ludwigshafen am Rhein, GermanyNutrition & Health Division, BASF SE, 67063 Ludwigshafen am Rhein, GermanyVitamin E, consisting of four tocopherols and four tocotrienols, with α-tocopherol as the most biologically active form, has a significant history in scientific research. It was first identified in the 1920s for its role in preventing neonatal mortality in rats. Over time, its chemical structure was elucidated, and its importance in the immune system, skin health, anti-inflammatory properties, and hormonal balance was revealed. Vitamin E production has evolved from natural sourcing to efficient synthesis with standardized potency units. Initially, animal studies focused on reproductive health and growth disorders, but later research highlighted vitamin E’s role in preventing encephalomalacia in domestic fowl and muscular dystrophy in various animals. Today, vitamin E is commonly used as a feed additive to enhance animal health and immune function. Despite substantial knowledge about its role in animal nutrition, several questions remain unanswered. Current research seeks to determine optimal supplementation levels, interactions with other nutrients, impacts on gene expression, cell signaling, and communication, as well as the effects of high dosages in livestock. Vitamin E continues to be a crucial component in improving animal health, and ongoing research aims to uncover its benefits and mechanisms of action further.https://www.mdpi.com/2077-0472/13/8/1526vitamin Ehistoryanimal nutritionproductionactivity |
| spellingShingle | Yauheni Shastak Ute Obermueller-Jevic Wolf Pelletier A Century of Vitamin E: Early Milestones and Future Directions in Animal Nutrition Agriculture vitamin E history animal nutrition production activity |
| title | A Century of Vitamin E: Early Milestones and Future Directions in Animal Nutrition |
| title_full | A Century of Vitamin E: Early Milestones and Future Directions in Animal Nutrition |
| title_fullStr | A Century of Vitamin E: Early Milestones and Future Directions in Animal Nutrition |
| title_full_unstemmed | A Century of Vitamin E: Early Milestones and Future Directions in Animal Nutrition |
| title_short | A Century of Vitamin E: Early Milestones and Future Directions in Animal Nutrition |
| title_sort | century of vitamin e early milestones and future directions in animal nutrition |
| topic | vitamin E history animal nutrition production activity |
| url | https://www.mdpi.com/2077-0472/13/8/1526 |
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