Role of inhibiting LIM-kinase2 in improving erectile function through suppression of corporal fibrosis in a rat model of cavernous nerve injury

Role of inhibiting LIM-kinase2 in improving erectile function through suppression of corporal fibrosis in a rat model of cavernous nerve injury

We evaluated whether LIM-kinase 2 inhibitor (LIMK2i) could improve erectile function by suppressing corporal fibrosis through the normalization of the Rho-associated coiled-coil protein kinase 1 (ROCK1)/LIMK2/Cofilin pathway in a rat model of cavernous nerve crush injury (CNCI). Sixty 11-week-old ma...

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Bibliographic Details
Main Authors:	Juhyun Park, Sung Yong Cho, Kwanjin Park, Ji Sun Chai, Hwancheol Son, Soo Woong Kim, Jae-Seung Paick, Min Chul Cho
Format:	Article
Language:	English
Published:	Wolters Kluwer Medknow Publications 2018-01-01
Series:	Asian Journal of Andrology
Subjects:	erectile dysfunction; fibrosis; LIM kinase; penis; prostatectomy
Online Access:	http://www.ajandrology.com/article.asp?issn=1008-682X;year=2018;volume=20;issue=4;spage=372;epage=378;aulast=Park

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