ZEB2/TWIST1/PRMT5/NuRD Multicomplex Contributes to the Epigenetic Regulation of EMT and Metastasis in Colorectal Carcinoma

ZEB2/TWIST1/PRMT5/NuRD Multicomplex Contributes to the Epigenetic Regulation of EMT and Metastasis in Colorectal Carcinoma

(1) Background: The EMT plays a crucial role in tumor metastasis, which is the major cause for colorectal carcinoma-related mortality. However, the underlying regulators and mechanisms of EMT in CRC metastasis are still poorly understood; (2) Methods: The transcriptional regulators of EMT in CRC and...

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Bibliographic Details
Main Authors: Yayuan Zheng, Mingrui Dai, Yue Dong, Hanqiao Yu, Tianfu Liu, Xuejian Feng, Bin Yu, Haihong Zhang, Jiaxin Wu, Wei Kong, Xianghui Yu, Hui Wu
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Cancers
Subjects:
colorectal cancer
ZEB2
TWIST1
E-cadherin
epithelial-mesenchymal transition
tumor metastasis
Online Access:https://www.mdpi.com/2072-6694/14/14/3426

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