Alpha-smooth muscle actin-positive cancer-associated fibroblasts secreting osteopontin promote growth of luminal breast cancer

Alpha-smooth muscle actin-positive cancer-associated fibroblasts secreting osteopontin promote growth of luminal breast cancer

Abstract Background Cancer-associated fibroblasts (CAFs) have been shown to support tumor development in a variety of cancers. Different markers were applied to classify CAFs in order to elucidate their impact on tumor progression. However, the exact mechanism by which CAFs enhance cancer developmen...

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Detalhes bibliográficos
Main Authors: Anna Muchlińska, Anna Nagel, Marta Popęda, Jolanta Szade, Magdalena Niemira, Jacek Zieliński, Jarosław Skokowski, Natalia Bednarz-Knoll, Anna J. Żaczek
Formato: Artigo
Idioma:English
Publicado em: BMC 2022-06-01
Colecção:Cellular & Molecular Biology Letters
Assuntos:
Cancer-associated fibroblast
Luminal breast cancer
Alpha-smooth muscle actin
Osteopontin
Acesso em linha:https://doi.org/10.1186/s11658-022-00351-7

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