Potential toxic effects of titanium dioxide nanoparticles and carbon nanotubes on land snail Helix aspersa: use of oxidative stress as a reliable biomarker for ecotoxicology assessment
Oxidative stress represents a main regularly informed mechanism of nanoparticles (NPs) toxicity. The present work was designed to evaluate the oxidative stress in haemolymph and digestive gland of snail Helix aspersa after exposure to different dermal doses: 10.8 and 2.17 µg snail-1 for titanium dio...
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| Format: | Article |
| Language: | English |
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University of Modena and Reggio Emilia
2021-10-01
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| Series: | Invertebrate Survival Journal |
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| Online Access: | https://www.isj.unimore.it/index.php/ISJ/article/view/694 |
| _version_ | 1818889717577416704 |
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| author | K Y Abdel-Halim S R Osman H T M El-Danasoury R M Ziada |
| author_facet | K Y Abdel-Halim S R Osman H T M El-Danasoury R M Ziada |
| author_sort | K Y Abdel-Halim |
| collection | DOAJ |
| description | Oxidative stress represents a main regularly informed mechanism of nanoparticles (NPs) toxicity. The present work was designed to evaluate the oxidative stress in haemolymph and digestive gland of snail Helix aspersa after exposure to different dermal doses: 10.8 and 2.17 µg snail-1 for titanium dioxide nanoparticles (TiO2NPs), and 8.0 and 1.6 µg snail-1 for Single-Walled Carbon Nanotubes (SWCNTs) during 48 h. The results indicated that, both nanomaterials (NMs) induced significant increases in malondialdehyde (MDA) as biomarker for lipid peroxidation (LPO). However, SWCNTs induced significant decline in reduced glutathione (GSH) content compared with the control. Catalase (CAT) activity significantly increased for the all treatments greater than the control. On the other hand, activities of glutathione-S-transferase (GST) and glutathione peroxidase (GPx) slightly decreased for both NMs. Nanoparticles (NPs) of TiO2 increased activity of glutathione reductase (GR) in both haemolymph and digestive gland homogenates, while SWCNTs treatments exhibited activities did not exceed the value of the control (0.08 U mg-1 protein). The present findings indicate that, alterations of antioxidant enzymes activity and levels of MDA and GSH are recognized to oxidative stress. Consequently, the use of snail, H. aspersa can offer a respectable sentinel model to assess ecotoxicological effects of NMs on the gastropods. |
| first_indexed | 2024-12-19T17:13:28Z |
| format | Article |
| id | doaj.art-bcb309bdaa0844078e30d135a61118d2 |
| institution | Directory Open Access Journal |
| issn | 1824-307X |
| language | English |
| last_indexed | 2024-12-19T17:13:28Z |
| publishDate | 2021-10-01 |
| publisher | University of Modena and Reggio Emilia |
| record_format | Article |
| series | Invertebrate Survival Journal |
| spelling | doaj.art-bcb309bdaa0844078e30d135a61118d22022-12-21T20:12:57ZengUniversity of Modena and Reggio EmiliaInvertebrate Survival Journal1824-307X2021-10-0118110.25431/1824-307X/isj.v18i1.119-129Potential toxic effects of titanium dioxide nanoparticles and carbon nanotubes on land snail Helix aspersa: use of oxidative stress as a reliable biomarker for ecotoxicology assessmentK Y Abdel-Halim0S R Osman1H T M El-Danasoury2R M Ziada3Mammalian and Aquatic Toxicology Department, Central Agricultural Pesticides Laboratory (CAPL), Agricultural Research Center (ARC), 12618-Dokki, Giza, EgyptMammalian and Aquatic Toxicology Department, Central Agricultural Pesticides Laboratory (CAPL), Agricultural Research Center (ARC), 12618-Dokki, Giza, EgyptDepartment of Plant Protection, Faculty of Agriculture, Suez Canal University, Ismailia, EgyptMammalian and Aquatic Toxicology Department, Central Agricultural Pesticides Laboratory (CAPL), Agricultural Research Center (ARC), 12618-Dokki, Giza, EgyptOxidative stress represents a main regularly informed mechanism of nanoparticles (NPs) toxicity. The present work was designed to evaluate the oxidative stress in haemolymph and digestive gland of snail Helix aspersa after exposure to different dermal doses: 10.8 and 2.17 µg snail-1 for titanium dioxide nanoparticles (TiO2NPs), and 8.0 and 1.6 µg snail-1 for Single-Walled Carbon Nanotubes (SWCNTs) during 48 h. The results indicated that, both nanomaterials (NMs) induced significant increases in malondialdehyde (MDA) as biomarker for lipid peroxidation (LPO). However, SWCNTs induced significant decline in reduced glutathione (GSH) content compared with the control. Catalase (CAT) activity significantly increased for the all treatments greater than the control. On the other hand, activities of glutathione-S-transferase (GST) and glutathione peroxidase (GPx) slightly decreased for both NMs. Nanoparticles (NPs) of TiO2 increased activity of glutathione reductase (GR) in both haemolymph and digestive gland homogenates, while SWCNTs treatments exhibited activities did not exceed the value of the control (0.08 U mg-1 protein). The present findings indicate that, alterations of antioxidant enzymes activity and levels of MDA and GSH are recognized to oxidative stress. Consequently, the use of snail, H. aspersa can offer a respectable sentinel model to assess ecotoxicological effects of NMs on the gastropods.https://www.isj.unimore.it/index.php/ISJ/article/view/694nanomaterialsoxidative stressterrestrialHelix aspersadermal toxicity |
| spellingShingle | K Y Abdel-Halim S R Osman H T M El-Danasoury R M Ziada Potential toxic effects of titanium dioxide nanoparticles and carbon nanotubes on land snail Helix aspersa: use of oxidative stress as a reliable biomarker for ecotoxicology assessment Invertebrate Survival Journal nanomaterials oxidative stress terrestrial Helix aspersa dermal toxicity |
| title | Potential toxic effects of titanium dioxide nanoparticles and carbon nanotubes on land snail Helix aspersa: use of oxidative stress as a reliable biomarker for ecotoxicology assessment |
| title_full | Potential toxic effects of titanium dioxide nanoparticles and carbon nanotubes on land snail Helix aspersa: use of oxidative stress as a reliable biomarker for ecotoxicology assessment |
| title_fullStr | Potential toxic effects of titanium dioxide nanoparticles and carbon nanotubes on land snail Helix aspersa: use of oxidative stress as a reliable biomarker for ecotoxicology assessment |
| title_full_unstemmed | Potential toxic effects of titanium dioxide nanoparticles and carbon nanotubes on land snail Helix aspersa: use of oxidative stress as a reliable biomarker for ecotoxicology assessment |
| title_short | Potential toxic effects of titanium dioxide nanoparticles and carbon nanotubes on land snail Helix aspersa: use of oxidative stress as a reliable biomarker for ecotoxicology assessment |
| title_sort | potential toxic effects of titanium dioxide nanoparticles and carbon nanotubes on land snail helix aspersa use of oxidative stress as a reliable biomarker for ecotoxicology assessment |
| topic | nanomaterials oxidative stress terrestrial Helix aspersa dermal toxicity |
| url | https://www.isj.unimore.it/index.php/ISJ/article/view/694 |
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