Association of insulin-like growth factor I gene polymorphisms (IGF1/TasI and IGF1/SnaBI) with the growth and subsequent milk yield of Polish Holstein-Friesian heifers
The aim of this study was to estimate potential relationships between insulin-like growth factor I gene polymorphisms (IGF1/TasI and IGF1/SnaBI) and the growth parameters of calves as well as their subsequent milk performance. The study involved a total of 191 Polish Holstein-Friesian var. Black-and...
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| Format: | Article |
| Language: | English |
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Czech Academy of Agricultural Sciences
2013-09-01
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| Series: | Czech Journal of Animal Science |
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| Online Access: | https://cjas.agriculturejournals.cz/artkey/cjs-201309-0003_association-of-insulin-like-growth-factor-i-gene-polymorphisms-igf1-tasi-and-igf1-snabi-with-the-growth-and-s.php |
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| author | M. Szewczuk M. Bajurna S. Zych W. Kruszyński |
| author_facet | M. Szewczuk M. Bajurna S. Zych W. Kruszyński |
| author_sort | M. Szewczuk |
| collection | DOAJ |
| description | The aim of this study was to estimate potential relationships between insulin-like growth factor I gene polymorphisms (IGF1/TasI and IGF1/SnaBI) and the growth parameters of calves as well as their subsequent milk performance. The study involved a total of 191 Polish Holstein-Friesian var. Black-and-White calves. Both polymorphic sites were determined with Amplification Created Restriction Sites-Polymerase Chain Reaction (ACRS-PCR). In the case of the IGF1/SnaBI polymorphism, the genotype and allele frequencies were as follows: TT - 0.27, CT - 0.55, CC - 0.18, T - 0.54, and C - 0.46. The CC genotype was favourable and associated with higher body weight at the 2nd month of age of calves (WT60) and their daily body weight gains from the 1st to the 2nd month (P ≤ 0.05) as well as subsequent milk, fat, and protein yield (P ≤ 0.01). For the IGF1/TasI polymorphism, the highest frequency of the AA genotype (0.69) was found. Allele frequencies were 0.75 and 0.25 for the A and C alleles, respectively. In the association study, the AC genotype was significantly associated with higher WT60 and average daily gains in the periods from the 2nd to the 3rd month of age and for the whole rearing period (P ≤ 0.05) as well as subsequent milk, fat, and protein yield (P ≤ 0.01). Combined genotypes were also included into the analysis. The highest yields of milk as well as fat and protein were found in cows with the CC/AA combination. No clear relationships between body weight and genotype combination were found. |
| first_indexed | 2024-04-10T08:26:30Z |
| format | Article |
| id | doaj.art-bcb4eeecf8914795baa262e61d23f3e8 |
| institution | Directory Open Access Journal |
| issn | 1212-1819 1805-9309 |
| language | English |
| last_indexed | 2024-04-10T08:26:30Z |
| publishDate | 2013-09-01 |
| publisher | Czech Academy of Agricultural Sciences |
| record_format | Article |
| series | Czech Journal of Animal Science |
| spelling | doaj.art-bcb4eeecf8914795baa262e61d23f3e82023-02-23T03:33:06ZengCzech Academy of Agricultural SciencesCzech Journal of Animal Science1212-18191805-93092013-09-0158940441110.17221/6940-CJAScjs-201309-0003Association of insulin-like growth factor I gene polymorphisms (IGF1/TasI and IGF1/SnaBI) with the growth and subsequent milk yield of Polish Holstein-Friesian heifersM. Szewczuk0M. Bajurna1S. Zych2W. Kruszyński3Laboratory of Molecular Cytogenetics, Department of Ruminant Science, The West Pomeranian University of Technology, Szczecin, PolandLaboratory of Molecular Cytogenetics, Department of Ruminant Science, The West Pomeranian University of Technology, Szczecin, PolandLaboratory of Veterinary Diagnostics LaboWet, Szczecin, PolandDivision of Animal Breeding and Cytogenetics, Department of Genetics, Wrocław University of Environmental and Life Sciences, Wroclaw, PolandThe aim of this study was to estimate potential relationships between insulin-like growth factor I gene polymorphisms (IGF1/TasI and IGF1/SnaBI) and the growth parameters of calves as well as their subsequent milk performance. The study involved a total of 191 Polish Holstein-Friesian var. Black-and-White calves. Both polymorphic sites were determined with Amplification Created Restriction Sites-Polymerase Chain Reaction (ACRS-PCR). In the case of the IGF1/SnaBI polymorphism, the genotype and allele frequencies were as follows: TT - 0.27, CT - 0.55, CC - 0.18, T - 0.54, and C - 0.46. The CC genotype was favourable and associated with higher body weight at the 2nd month of age of calves (WT60) and their daily body weight gains from the 1st to the 2nd month (P ≤ 0.05) as well as subsequent milk, fat, and protein yield (P ≤ 0.01). For the IGF1/TasI polymorphism, the highest frequency of the AA genotype (0.69) was found. Allele frequencies were 0.75 and 0.25 for the A and C alleles, respectively. In the association study, the AC genotype was significantly associated with higher WT60 and average daily gains in the periods from the 2nd to the 3rd month of age and for the whole rearing period (P ≤ 0.05) as well as subsequent milk, fat, and protein yield (P ≤ 0.01). Combined genotypes were also included into the analysis. The highest yields of milk as well as fat and protein were found in cows with the CC/AA combination. No clear relationships between body weight and genotype combination were found.https://cjas.agriculturejournals.cz/artkey/cjs-201309-0003_association-of-insulin-like-growth-factor-i-gene-polymorphisms-igf1-tasi-and-igf1-snabi-with-the-growth-and-s.phpcattlebody weightinsulin-like growth factorsmilk performance |
| spellingShingle | M. Szewczuk M. Bajurna S. Zych W. Kruszyński Association of insulin-like growth factor I gene polymorphisms (IGF1/TasI and IGF1/SnaBI) with the growth and subsequent milk yield of Polish Holstein-Friesian heifers Czech Journal of Animal Science cattle body weight insulin-like growth factors milk performance |
| title | Association of insulin-like growth factor I gene polymorphisms (IGF1/TasI and IGF1/SnaBI) with the growth and subsequent milk yield of Polish Holstein-Friesian heifers |
| title_full | Association of insulin-like growth factor I gene polymorphisms (IGF1/TasI and IGF1/SnaBI) with the growth and subsequent milk yield of Polish Holstein-Friesian heifers |
| title_fullStr | Association of insulin-like growth factor I gene polymorphisms (IGF1/TasI and IGF1/SnaBI) with the growth and subsequent milk yield of Polish Holstein-Friesian heifers |
| title_full_unstemmed | Association of insulin-like growth factor I gene polymorphisms (IGF1/TasI and IGF1/SnaBI) with the growth and subsequent milk yield of Polish Holstein-Friesian heifers |
| title_short | Association of insulin-like growth factor I gene polymorphisms (IGF1/TasI and IGF1/SnaBI) with the growth and subsequent milk yield of Polish Holstein-Friesian heifers |
| title_sort | association of insulin like growth factor i gene polymorphisms igf1 tasi and igf1 snabi with the growth and subsequent milk yield of polish holstein friesian heifers |
| topic | cattle body weight insulin-like growth factors milk performance |
| url | https://cjas.agriculturejournals.cz/artkey/cjs-201309-0003_association-of-insulin-like-growth-factor-i-gene-polymorphisms-igf1-tasi-and-igf1-snabi-with-the-growth-and-s.php |
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