Small lymphocytic lymphoma of the prostate mimicking a PIRADS 5 lesion that resolved after systemic treatment
Prostatic PIRADS 4 and 5 lesions on multiparametric MRI typically represent adenocarcinoma with small lymphocytic lymphoma being a rare pathological finding. We report a case of small lymphocytic lymphoma masquerading as PIRADS 4 and 5 lesions with associated lymphadenopathy in a 69-year-old male on...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-11-01
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| Series: | Urology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214442021002151 |
| _version_ | 1819132006851674112 |
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| author | Tiffany H. Wong David Ambinder Milana Flusberg Fouzia Shakil John L. Phillips Nathan C. Wong |
| author_facet | Tiffany H. Wong David Ambinder Milana Flusberg Fouzia Shakil John L. Phillips Nathan C. Wong |
| author_sort | Tiffany H. Wong |
| collection | DOAJ |
| description | Prostatic PIRADS 4 and 5 lesions on multiparametric MRI typically represent adenocarcinoma with small lymphocytic lymphoma being a rare pathological finding. We report a case of small lymphocytic lymphoma masquerading as PIRADS 4 and 5 lesions with associated lymphadenopathy in a 69-year-old male on active surveillance for low-risk prostate cancer that was subsequently confirmed on targeted and systematic prostate biopsy. Following treatment of lymphoma with ibrutinib, there was complete resolution of the PIRADS lesions on follow-up mpMRI. |
| first_indexed | 2024-12-22T09:24:33Z |
| format | Article |
| id | doaj.art-bcb5421a887a4b69a2ba84076204bd2c |
| institution | Directory Open Access Journal |
| issn | 2214-4420 |
| language | English |
| last_indexed | 2024-12-22T09:24:33Z |
| publishDate | 2021-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Urology Case Reports |
| spelling | doaj.art-bcb5421a887a4b69a2ba84076204bd2c2022-12-21T18:31:06ZengElsevierUrology Case Reports2214-44202021-11-0139101775Small lymphocytic lymphoma of the prostate mimicking a PIRADS 5 lesion that resolved after systemic treatmentTiffany H. Wong0David Ambinder1Milana Flusberg2Fouzia Shakil3John L. Phillips4Nathan C. Wong5New York Medical College, Valhalla, NY, USANew York Medical College, Valhalla, NY, USA; Department of Urology, Westchester Medical Center, Valhalla, NY, 10595, USANew York Medical College, Valhalla, NY, USA; Department of Radiology, Westchester Medical Center, Valhalla, NY, 10595, USANew York Medical College, Valhalla, NY, USA; Department of Pathology, Westchester Medical Center, Valhalla, NY, 10595, USANew York Medical College, Valhalla, NY, USA; Department of Urology, Westchester Medical Center, Valhalla, NY, 10595, USANew York Medical College, Valhalla, NY, USA; Department of Urology, Westchester Medical Center, Valhalla, NY, 10595, USA; Corresponding author. Department of Urology, Westchester Medical Center, Valhalla, NY, 10595, USA.Prostatic PIRADS 4 and 5 lesions on multiparametric MRI typically represent adenocarcinoma with small lymphocytic lymphoma being a rare pathological finding. We report a case of small lymphocytic lymphoma masquerading as PIRADS 4 and 5 lesions with associated lymphadenopathy in a 69-year-old male on active surveillance for low-risk prostate cancer that was subsequently confirmed on targeted and systematic prostate biopsy. Following treatment of lymphoma with ibrutinib, there was complete resolution of the PIRADS lesions on follow-up mpMRI.http://www.sciencedirect.com/science/article/pii/S2214442021002151Small lymphocytic leukemiaChronic lymphocytic leukemiaProstatic lymphomaMagnetic resonance imaging |
| spellingShingle | Tiffany H. Wong David Ambinder Milana Flusberg Fouzia Shakil John L. Phillips Nathan C. Wong Small lymphocytic lymphoma of the prostate mimicking a PIRADS 5 lesion that resolved after systemic treatment Urology Case Reports Small lymphocytic leukemia Chronic lymphocytic leukemia Prostatic lymphoma Magnetic resonance imaging |
| title | Small lymphocytic lymphoma of the prostate mimicking a PIRADS 5 lesion that resolved after systemic treatment |
| title_full | Small lymphocytic lymphoma of the prostate mimicking a PIRADS 5 lesion that resolved after systemic treatment |
| title_fullStr | Small lymphocytic lymphoma of the prostate mimicking a PIRADS 5 lesion that resolved after systemic treatment |
| title_full_unstemmed | Small lymphocytic lymphoma of the prostate mimicking a PIRADS 5 lesion that resolved after systemic treatment |
| title_short | Small lymphocytic lymphoma of the prostate mimicking a PIRADS 5 lesion that resolved after systemic treatment |
| title_sort | small lymphocytic lymphoma of the prostate mimicking a pirads 5 lesion that resolved after systemic treatment |
| topic | Small lymphocytic leukemia Chronic lymphocytic leukemia Prostatic lymphoma Magnetic resonance imaging |
| url | http://www.sciencedirect.com/science/article/pii/S2214442021002151 |
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