Automated Diabetic Retinopathy Detection Based on Binocular Siamese-Like Convolutional Neural Network

Diabetic retinopathy (DR) is an important cause of blindness worldwide. However, DR is hard to be detected in the early stages, and the diagnostic procedure can be time-consuming even for the experienced experts. Therefore, a computer-aided diagnosis method based on deep learning algorithms is propo...

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Main Authors: Xianglong Zeng, Haiquan Chen, Yuan Luo, Wenbin Ye
Format: Article
Language:English
Published: IEEE 2019-01-01
Series:IEEE Access
Subjects:
Online Access:https://ieeexplore.ieee.org/document/8660434/
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author Xianglong Zeng
Haiquan Chen
Yuan Luo
Wenbin Ye
author_facet Xianglong Zeng
Haiquan Chen
Yuan Luo
Wenbin Ye
author_sort Xianglong Zeng
collection DOAJ
description Diabetic retinopathy (DR) is an important cause of blindness worldwide. However, DR is hard to be detected in the early stages, and the diagnostic procedure can be time-consuming even for the experienced experts. Therefore, a computer-aided diagnosis method based on deep learning algorithms is proposed to automatedly diagnose the referable diabetic retinopathy by classifying color retinal fundus photographs into two grades. In this paper, a novel convolutional neural network model with the Siamese-like architecture is trained with a transfer learning technique. Different from the previous works, the proposed model accepts binocular fundus images as inputs and learns their correlation to help to make a prediction. In the case with a training set of only 28 104 images and a test set of 7024 images, an area under the receiver operating curve of 0.951 is obtained by the proposed binocular model, which is 0.011 higher than that obtained by the existing monocular model. To further verify the effectiveness of the binocular design, a binocular model for five-class DR detection is also trained and evaluated on a 10% validation set. The result shows that it achieves a kappa score of 0.829 which is higher than that of the existing non-ensemble model.
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spelling doaj.art-bcb739dff9424d7b82f284def84026ae2022-12-21T23:05:26ZengIEEEIEEE Access2169-35362019-01-017307443075310.1109/ACCESS.2019.29031718660434Automated Diabetic Retinopathy Detection Based on Binocular Siamese-Like Convolutional Neural NetworkXianglong Zeng0Haiquan Chen1Yuan Luo2Wenbin Ye3https://orcid.org/0000-0001-6978-813XSchool of Optoelectronic Engineering, Shenzhen University, Shenzhen, ChinaSchool of Optoelectronic Engineering, Shenzhen University, Shenzhen, ChinaSchool of Electronic Science and Technology, Shenzhen University, Shenzhen, ChinaSchool of Electronic Science and Technology, Shenzhen University, Shenzhen, ChinaDiabetic retinopathy (DR) is an important cause of blindness worldwide. However, DR is hard to be detected in the early stages, and the diagnostic procedure can be time-consuming even for the experienced experts. Therefore, a computer-aided diagnosis method based on deep learning algorithms is proposed to automatedly diagnose the referable diabetic retinopathy by classifying color retinal fundus photographs into two grades. In this paper, a novel convolutional neural network model with the Siamese-like architecture is trained with a transfer learning technique. Different from the previous works, the proposed model accepts binocular fundus images as inputs and learns their correlation to help to make a prediction. In the case with a training set of only 28 104 images and a test set of 7024 images, an area under the receiver operating curve of 0.951 is obtained by the proposed binocular model, which is 0.011 higher than that obtained by the existing monocular model. To further verify the effectiveness of the binocular design, a binocular model for five-class DR detection is also trained and evaluated on a 10% validation set. The result shows that it achieves a kappa score of 0.829 which is higher than that of the existing non-ensemble model.https://ieeexplore.ieee.org/document/8660434/Biomedical imaging processingdiabetic retinopathyfundus photographconvolutional neural networkdeep learningSiamese-like network
spellingShingle Xianglong Zeng
Haiquan Chen
Yuan Luo
Wenbin Ye
Automated Diabetic Retinopathy Detection Based on Binocular Siamese-Like Convolutional Neural Network
IEEE Access
Biomedical imaging processing
diabetic retinopathy
fundus photograph
convolutional neural network
deep learning
Siamese-like network
title Automated Diabetic Retinopathy Detection Based on Binocular Siamese-Like Convolutional Neural Network
title_full Automated Diabetic Retinopathy Detection Based on Binocular Siamese-Like Convolutional Neural Network
title_fullStr Automated Diabetic Retinopathy Detection Based on Binocular Siamese-Like Convolutional Neural Network
title_full_unstemmed Automated Diabetic Retinopathy Detection Based on Binocular Siamese-Like Convolutional Neural Network
title_short Automated Diabetic Retinopathy Detection Based on Binocular Siamese-Like Convolutional Neural Network
title_sort automated diabetic retinopathy detection based on binocular siamese like convolutional neural network
topic Biomedical imaging processing
diabetic retinopathy
fundus photograph
convolutional neural network
deep learning
Siamese-like network
url https://ieeexplore.ieee.org/document/8660434/
work_keys_str_mv AT xianglongzeng automateddiabeticretinopathydetectionbasedonbinocularsiameselikeconvolutionalneuralnetwork
AT haiquanchen automateddiabeticretinopathydetectionbasedonbinocularsiameselikeconvolutionalneuralnetwork
AT yuanluo automateddiabeticretinopathydetectionbasedonbinocularsiameselikeconvolutionalneuralnetwork
AT wenbinye automateddiabeticretinopathydetectionbasedonbinocularsiameselikeconvolutionalneuralnetwork