A Group of Complexes Based on PAMAM and Quantum Dots Used in Clinical Immunoassays
Abstract We report a group of complexes used in clinical immunoassays. The complexes include a PAMAM-conjugated goat anti-rabbit IgG and a QDs-conjugated goat anti-mouse IgG. When rabbit anti-antigen and mouse anti-antigen are added, the corresponding antigen will be detected. The experiment, using...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SpringerOpen
2020-04-01
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| Series: | Nanoscale Research Letters |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s11671-020-3291-5 |
| _version_ | 1797715464498970624 |
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| author | Yang Liu Lu Hou Qiong Guo Mingjin Zhang Wei Shi |
| author_facet | Yang Liu Lu Hou Qiong Guo Mingjin Zhang Wei Shi |
| author_sort | Yang Liu |
| collection | DOAJ |
| description | Abstract We report a group of complexes used in clinical immunoassays. The complexes include a PAMAM-conjugated goat anti-rabbit IgG and a QDs-conjugated goat anti-mouse IgG. When rabbit anti-antigen and mouse anti-antigen are added, the corresponding antigen will be detected. The experiment, using the complexes, is simple, convenient, short in time, and short in steps. It is also applicable to different experiment methods, like to be used with FCM (flow cytometry), ICC (immunocytochemistry), and IHC (immunohistochemistry) to detect many kinds of antigens. |
| first_indexed | 2024-03-12T08:07:11Z |
| format | Article |
| id | doaj.art-bcc02e45eff1467a9999e728715cbbc9 |
| institution | Directory Open Access Journal |
| issn | 1556-276X |
| language | English |
| last_indexed | 2024-03-12T08:07:11Z |
| publishDate | 2020-04-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Nanoscale Research Letters |
| spelling | doaj.art-bcc02e45eff1467a9999e728715cbbc92023-09-02T19:26:07ZengSpringerOpenNanoscale Research Letters1556-276X2020-04-011511910.1186/s11671-020-3291-5A Group of Complexes Based on PAMAM and Quantum Dots Used in Clinical ImmunoassaysYang Liu0Lu Hou1Qiong Guo2Mingjin Zhang3Wei Shi4Key Laboratory for Molecular Enzymology & Engineering, the Ministry of Education, Jilin UniversityKey Laboratory for Molecular Enzymology & Engineering, the Ministry of Education, Jilin UniversityKey Laboratory for Molecular Enzymology & Engineering, the Ministry of Education, Jilin UniversityKey Laboratory for Molecular Enzymology & Engineering, the Ministry of Education, Jilin UniversityKey Laboratory for Molecular Enzymology & Engineering, the Ministry of Education, Jilin UniversityAbstract We report a group of complexes used in clinical immunoassays. The complexes include a PAMAM-conjugated goat anti-rabbit IgG and a QDs-conjugated goat anti-mouse IgG. When rabbit anti-antigen and mouse anti-antigen are added, the corresponding antigen will be detected. The experiment, using the complexes, is simple, convenient, short in time, and short in steps. It is also applicable to different experiment methods, like to be used with FCM (flow cytometry), ICC (immunocytochemistry), and IHC (immunohistochemistry) to detect many kinds of antigens.http://link.springer.com/article/10.1186/s11671-020-3291-5PAMAMQuantum dotsClinical immunoassaysFCM |
| spellingShingle | Yang Liu Lu Hou Qiong Guo Mingjin Zhang Wei Shi A Group of Complexes Based on PAMAM and Quantum Dots Used in Clinical Immunoassays Nanoscale Research Letters PAMAM Quantum dots Clinical immunoassays FCM |
| title | A Group of Complexes Based on PAMAM and Quantum Dots Used in Clinical Immunoassays |
| title_full | A Group of Complexes Based on PAMAM and Quantum Dots Used in Clinical Immunoassays |
| title_fullStr | A Group of Complexes Based on PAMAM and Quantum Dots Used in Clinical Immunoassays |
| title_full_unstemmed | A Group of Complexes Based on PAMAM and Quantum Dots Used in Clinical Immunoassays |
| title_short | A Group of Complexes Based on PAMAM and Quantum Dots Used in Clinical Immunoassays |
| title_sort | group of complexes based on pamam and quantum dots used in clinical immunoassays |
| topic | PAMAM Quantum dots Clinical immunoassays FCM |
| url | http://link.springer.com/article/10.1186/s11671-020-3291-5 |
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