Effect of dietary supplementation of humic acid and lincomycin on growth performance, nutrient digestibility, blood biochemistry, and gut morphology in broilers under clostridium infection
Five hundred and sixty broilers were placed into seven groups. The first negative control (A) was fed the baseline diet (BD); the second positive control (B) was fed BD and exposed to clostridium infection; and the third and fourth groups (C, D) were the same as the positive control with 500 and 100...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2022-12-01
|
| Series: | Journal of Applied Animal Research |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/09712119.2022.2089674 |
| _version_ | 1811239169818624000 |
|---|---|
| author | Ahmed A. Saleh Mohamed Yassin Karima El-Naggar Mohammed H. Alzawqari Sarah Albogami Mohamed Mohamed Soliman Mustafa Shukry Foad Farrag Abeer A. Kirrella |
| author_facet | Ahmed A. Saleh Mohamed Yassin Karima El-Naggar Mohammed H. Alzawqari Sarah Albogami Mohamed Mohamed Soliman Mustafa Shukry Foad Farrag Abeer A. Kirrella |
| author_sort | Ahmed A. Saleh |
| collection | DOAJ |
| description | Five hundred and sixty broilers were placed into seven groups. The first negative control (A) was fed the baseline diet (BD); the second positive control (B) was fed BD and exposed to clostridium infection; and the third and fourth groups (C, D) were the same as the positive control with 500 and 1000 g/ton of feed, respectively. The fifth group (E) served as a positive control for the addition of lincomycin, whereas the sixth and seventh groups (F, G) received the same designed diet as the E group but supplemented with HA at 500 and 1000 g/ton of feed, respectively. Birds infected with Clostridium perfringens had considerably decreased body weight. However, a dietary combination of HA and lincomycin resulted in a greater improvement in growth. Body weight increased after 35 days, but feed intake dropped, therefore HA and lincomycin supplementation enhanced feed conversion ratio. Supplementing with HA and lincomycin increased crude protein retention. Furthermore, these additions mitigated the detrimental effects of clostridial infection on the gut by reducing degenerative changes in intestinal villi and increasing villi length, particularly at higher HA/lincomycin doses. In conclusion, nutritional supplementation with humic acid and lincomycin improved blood biochemistry, and gut morphology in broilers infected with Clostridium difficile. |
| first_indexed | 2024-04-12T12:55:07Z |
| format | Article |
| id | doaj.art-bcc02feef437455780b72af44e1a653d |
| institution | Directory Open Access Journal |
| issn | 0971-2119 0974-1844 |
| language | English |
| last_indexed | 2024-04-12T12:55:07Z |
| publishDate | 2022-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Applied Animal Research |
| spelling | doaj.art-bcc02feef437455780b72af44e1a653d2022-12-22T03:32:21ZengTaylor & Francis GroupJournal of Applied Animal Research0971-21190974-18442022-12-0150144045210.1080/09712119.2022.2089674Effect of dietary supplementation of humic acid and lincomycin on growth performance, nutrient digestibility, blood biochemistry, and gut morphology in broilers under clostridium infectionAhmed A. Saleh0Mohamed Yassin1Karima El-Naggar2Mohammed H. Alzawqari3Sarah Albogami4Mohamed Mohamed Soliman5Mustafa Shukry6Foad Farrag7Abeer A. Kirrella8Department of Poultry Production, Faculty of Agriculture, Kafrelsheikh University, Kafrelsheikh, EgyptDepartment of Poultry Production, Faculty of Agriculture, Kafrelsheikh University, Kafrelsheikh, EgyptDepartment of Nutrition and Veterinary Clinical Nutrition, Faculty of Veterinary Medicine, Alexandria University, Alexandrina, EgyptDepartment of Poultry Production, Faculty of Agriculture, Kafrelsheikh University, Kafrelsheikh, EgyptDepartment of Biotechnology, College of Science, Taif University, Taif, Saudi ArabiaClinical Laboratory Sciences Department, Turabah University College, Taif University, Taif, Saudi ArabiaDepartment of Physiology, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafrelsheikh, EgyptDepartment of Anatomy and Embryology, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafrelsheikh, EgyptDepartment of Poultry Production, Faculty of Agriculture, Kafrelsheikh University, Kafrelsheikh, EgyptFive hundred and sixty broilers were placed into seven groups. The first negative control (A) was fed the baseline diet (BD); the second positive control (B) was fed BD and exposed to clostridium infection; and the third and fourth groups (C, D) were the same as the positive control with 500 and 1000 g/ton of feed, respectively. The fifth group (E) served as a positive control for the addition of lincomycin, whereas the sixth and seventh groups (F, G) received the same designed diet as the E group but supplemented with HA at 500 and 1000 g/ton of feed, respectively. Birds infected with Clostridium perfringens had considerably decreased body weight. However, a dietary combination of HA and lincomycin resulted in a greater improvement in growth. Body weight increased after 35 days, but feed intake dropped, therefore HA and lincomycin supplementation enhanced feed conversion ratio. Supplementing with HA and lincomycin increased crude protein retention. Furthermore, these additions mitigated the detrimental effects of clostridial infection on the gut by reducing degenerative changes in intestinal villi and increasing villi length, particularly at higher HA/lincomycin doses. In conclusion, nutritional supplementation with humic acid and lincomycin improved blood biochemistry, and gut morphology in broilers infected with Clostridium difficile.https://www.tandfonline.com/doi/10.1080/09712119.2022.2089674Humic acidlincomycinblood biochemistrygut morphologybroilers |
| spellingShingle | Ahmed A. Saleh Mohamed Yassin Karima El-Naggar Mohammed H. Alzawqari Sarah Albogami Mohamed Mohamed Soliman Mustafa Shukry Foad Farrag Abeer A. Kirrella Effect of dietary supplementation of humic acid and lincomycin on growth performance, nutrient digestibility, blood biochemistry, and gut morphology in broilers under clostridium infection Journal of Applied Animal Research Humic acid lincomycin blood biochemistry gut morphology broilers |
| title | Effect of dietary supplementation of humic acid and lincomycin on growth performance, nutrient digestibility, blood biochemistry, and gut morphology in broilers under clostridium infection |
| title_full | Effect of dietary supplementation of humic acid and lincomycin on growth performance, nutrient digestibility, blood biochemistry, and gut morphology in broilers under clostridium infection |
| title_fullStr | Effect of dietary supplementation of humic acid and lincomycin on growth performance, nutrient digestibility, blood biochemistry, and gut morphology in broilers under clostridium infection |
| title_full_unstemmed | Effect of dietary supplementation of humic acid and lincomycin on growth performance, nutrient digestibility, blood biochemistry, and gut morphology in broilers under clostridium infection |
| title_short | Effect of dietary supplementation of humic acid and lincomycin on growth performance, nutrient digestibility, blood biochemistry, and gut morphology in broilers under clostridium infection |
| title_sort | effect of dietary supplementation of humic acid and lincomycin on growth performance nutrient digestibility blood biochemistry and gut morphology in broilers under clostridium infection |
| topic | Humic acid lincomycin blood biochemistry gut morphology broilers |
| url | https://www.tandfonline.com/doi/10.1080/09712119.2022.2089674 |
| work_keys_str_mv | AT ahmedasaleh effectofdietarysupplementationofhumicacidandlincomycinongrowthperformancenutrientdigestibilitybloodbiochemistryandgutmorphologyinbroilersunderclostridiuminfection AT mohamedyassin effectofdietarysupplementationofhumicacidandlincomycinongrowthperformancenutrientdigestibilitybloodbiochemistryandgutmorphologyinbroilersunderclostridiuminfection AT karimaelnaggar effectofdietarysupplementationofhumicacidandlincomycinongrowthperformancenutrientdigestibilitybloodbiochemistryandgutmorphologyinbroilersunderclostridiuminfection AT mohammedhalzawqari effectofdietarysupplementationofhumicacidandlincomycinongrowthperformancenutrientdigestibilitybloodbiochemistryandgutmorphologyinbroilersunderclostridiuminfection AT sarahalbogami effectofdietarysupplementationofhumicacidandlincomycinongrowthperformancenutrientdigestibilitybloodbiochemistryandgutmorphologyinbroilersunderclostridiuminfection AT mohamedmohamedsoliman effectofdietarysupplementationofhumicacidandlincomycinongrowthperformancenutrientdigestibilitybloodbiochemistryandgutmorphologyinbroilersunderclostridiuminfection AT mustafashukry effectofdietarysupplementationofhumicacidandlincomycinongrowthperformancenutrientdigestibilitybloodbiochemistryandgutmorphologyinbroilersunderclostridiuminfection AT foadfarrag effectofdietarysupplementationofhumicacidandlincomycinongrowthperformancenutrientdigestibilitybloodbiochemistryandgutmorphologyinbroilersunderclostridiuminfection AT abeerakirrella effectofdietarysupplementationofhumicacidandlincomycinongrowthperformancenutrientdigestibilitybloodbiochemistryandgutmorphologyinbroilersunderclostridiuminfection |