A 16-Year Single-Center Series of Trachea Resections for Locally Advanced Thyroid Carcinoma
(1) Background: Infiltration of the aerodigestive tract in advanced thyroid carcinoma determines the prognosis and quality of life. Different stages of tracheal tumor invasion require customization of the surgical concept. (2) Methods: In the period from January 2007 to January 2023, patients who un...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-12-01
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| Series: | Cancers |
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| Online Access: | https://www.mdpi.com/2072-6694/16/1/163 |
| _version_ | 1797359024331554816 |
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| author | Julia I. Staubitz-Vernazza Sina Schwind Oana Lozan Thomas J. Musholt |
| author_facet | Julia I. Staubitz-Vernazza Sina Schwind Oana Lozan Thomas J. Musholt |
| author_sort | Julia I. Staubitz-Vernazza |
| collection | DOAJ |
| description | (1) Background: Infiltration of the aerodigestive tract in advanced thyroid carcinoma determines the prognosis and quality of life. Different stages of tracheal tumor invasion require customization of the surgical concept. (2) Methods: In the period from January 2007 to January 2023, patients who underwent surgery for advanced thyroid carcinomas with trachea resections were included in a retrospective observational study. The surgical resection concepts and operation-associated complications were documented. The overall survival and post-resection survival were analyzed. (3) Results: From 2007 to 2023, at the single-center UMC Mainz, 33 patients (15 female and 18 male) underwent neck surgery with trachea resections for locally advanced thyroid carcinomas. Of these, 14 were treated with non-transmural (trachea shaving) and 19 transmural trachea resections (9 “window” resections, 6 near-circular resections, 3 sleeve resections and 1 total laryngectomy with extramucosal esophageal resection). The two-year postoperative survival rate was 82.0 percent. The two-year recurrence-free survival rate was 75.0 percent (mean follow-up period: 29.2 months). (4) Conclusions: Tracheal resections for locally advanced tumor infiltration are feasible as an element of highly individualized treatment concepts. |
| first_indexed | 2024-03-08T15:10:42Z |
| format | Article |
| id | doaj.art-bcc0aabc46774b5ea3181be575965558 |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-08T15:10:42Z |
| publishDate | 2023-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-bcc0aabc46774b5ea3181be5759655582024-01-10T14:52:53ZengMDPI AGCancers2072-66942023-12-0116116310.3390/cancers16010163A 16-Year Single-Center Series of Trachea Resections for Locally Advanced Thyroid CarcinomaJulia I. Staubitz-Vernazza0Sina Schwind1Oana Lozan2Thomas J. Musholt3Section of Endocrine Surgery, Department of General, Visceral and Transplantation Surgery, University Medical Center, Johannes Gutenberg University Mainz, Langenbeckstraße 1, D-55131 Mainz, GermanySection of Endocrine Surgery, Department of General, Visceral and Transplantation Surgery, University Medical Center, Johannes Gutenberg University Mainz, Langenbeckstraße 1, D-55131 Mainz, GermanySection of Endocrine Surgery, Department of General, Visceral and Transplantation Surgery, University Medical Center, Johannes Gutenberg University Mainz, Langenbeckstraße 1, D-55131 Mainz, GermanySection of Endocrine Surgery, Department of General, Visceral and Transplantation Surgery, University Medical Center, Johannes Gutenberg University Mainz, Langenbeckstraße 1, D-55131 Mainz, Germany(1) Background: Infiltration of the aerodigestive tract in advanced thyroid carcinoma determines the prognosis and quality of life. Different stages of tracheal tumor invasion require customization of the surgical concept. (2) Methods: In the period from January 2007 to January 2023, patients who underwent surgery for advanced thyroid carcinomas with trachea resections were included in a retrospective observational study. The surgical resection concepts and operation-associated complications were documented. The overall survival and post-resection survival were analyzed. (3) Results: From 2007 to 2023, at the single-center UMC Mainz, 33 patients (15 female and 18 male) underwent neck surgery with trachea resections for locally advanced thyroid carcinomas. Of these, 14 were treated with non-transmural (trachea shaving) and 19 transmural trachea resections (9 “window” resections, 6 near-circular resections, 3 sleeve resections and 1 total laryngectomy with extramucosal esophageal resection). The two-year postoperative survival rate was 82.0 percent. The two-year recurrence-free survival rate was 75.0 percent (mean follow-up period: 29.2 months). (4) Conclusions: Tracheal resections for locally advanced tumor infiltration are feasible as an element of highly individualized treatment concepts.https://www.mdpi.com/2072-6694/16/1/163trachea infiltrationthyroid carcinomatrachea resection |
| spellingShingle | Julia I. Staubitz-Vernazza Sina Schwind Oana Lozan Thomas J. Musholt A 16-Year Single-Center Series of Trachea Resections for Locally Advanced Thyroid Carcinoma Cancers trachea infiltration thyroid carcinoma trachea resection |
| title | A 16-Year Single-Center Series of Trachea Resections for Locally Advanced Thyroid Carcinoma |
| title_full | A 16-Year Single-Center Series of Trachea Resections for Locally Advanced Thyroid Carcinoma |
| title_fullStr | A 16-Year Single-Center Series of Trachea Resections for Locally Advanced Thyroid Carcinoma |
| title_full_unstemmed | A 16-Year Single-Center Series of Trachea Resections for Locally Advanced Thyroid Carcinoma |
| title_short | A 16-Year Single-Center Series of Trachea Resections for Locally Advanced Thyroid Carcinoma |
| title_sort | 16 year single center series of trachea resections for locally advanced thyroid carcinoma |
| topic | trachea infiltration thyroid carcinoma trachea resection |
| url | https://www.mdpi.com/2072-6694/16/1/163 |
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