Hyaluronic Acid Hydrogels Hybridized With Au-Triptolide Nanoparticles for Intraarticular Targeted Multi-Therapy of Rheumatoid Arthritis

Hyaluronic Acid Hydrogels Hybridized With Au-Triptolide Nanoparticles for Intraarticular Targeted Multi-Therapy of Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a chronic inflammatory disease, characterized by synovial inflammation in multiple joints. Triptolide (TP) is a disease-modifying anti-rheumatic drug (DMARD) highly effective in patients with RA and has anti-inflammatory properties. However, its clinical application has...

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Bibliographic Details
Main Authors:	Chenxi Li, Rui Liu, Yurong Song, Youwen Chen, Dongjie Zhu, Liuchunyang Yu, Qingcai Huang, Zhengjia Zhang, Zeyu Xue, Zhenglai Hua, Cheng Lu, Aiping Lu, Yuanyan Liu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-05-01
Series:	Frontiers in Pharmacology
Subjects:	rheumatoid arthritis photothermal-chemo treatment NIR imaging mTOR/p70S6K pathway TP-PLGA-Au@RGD/HA hydrogels
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2022.849101/full

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