Arterial stiffness and risk factors of cardiovascular disease
Aim. To investigate arterial stiffness (AS) in healthy subjects and its correlation with standard cardiovascular risk factors (CRF). Material and methods. AS was estimated on Tensioclinic arteriograph (Tensiomed, Hungary) in 97 subjects (76 females and 21 males) having symptoms of neither atheroscle...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | Russian |
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"Consilium Medicum" Publishing house
2009-03-01
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| Series: | Терапевтический архив |
| Subjects: | |
| Online Access: | https://ter-arkhiv.ru/0040-3660/article/view/30299 |
| _version_ | 1818408455068712960 |
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| author | A P Rebrov N M Nikitina N A Karoli N A Magdeeva I A Kharitonova D A Kondakova A P Rebrov N M Nikitina N A Karoli N A Magdeeva I A Kharitonova D A Kondakova |
| author_facet | A P Rebrov N M Nikitina N A Karoli N A Magdeeva I A Kharitonova D A Kondakova A P Rebrov N M Nikitina N A Karoli N A Magdeeva I A Kharitonova D A Kondakova |
| author_sort | A P Rebrov |
| collection | DOAJ |
| description | Aim. To investigate arterial stiffness (AS) in healthy subjects and its correlation with standard cardiovascular risk factors (CRF).
Material and methods. AS was estimated on Tensioclinic arteriograph (Tensiomed, Hungary) in 97 subjects (76 females and 21 males) having symptoms of neither atherosclerosis nor coronary heart disease (CHD). Detection of CRF was made by questionnaire survey. 10-year CHD risk and cardiovascular death risk (SCORE) were estimated.
Results. With age, there was a rise of augmentation index (AI) (r = 0.76; p < 0.001) and pulse wave velocity (PWV) in the aorta (r = 0.61; p < 0.001), AI changes arose earlier than those of aortic PWV. Arterial hypertension is an independent factor of arterial stiffness deterioration. High blood cholesterol, AS, body mass index, smoking index directly correlate with AI and PWV in young subjects. CHD risk and SCORE rise with an AS increase (r = 0.30; p < 0.05 and r = 0.34; p < 0.05, respectively).
Conclusion. Of CRF, most significant determinant of AS are arterial hypertension and age. AI is a more sensitive marker of AS in young subjects. Increased aortic PWV is more typical for persons over 50 years of age. The study of pulse wave characteristics with application of Tensioclinic arteriograph is a simple and significant method of detecting early changes in AS. |
| first_indexed | 2024-12-14T09:44:00Z |
| format | Article |
| id | doaj.art-bcc22a54c53a4da28f60894fee3f0e4f |
| institution | Directory Open Access Journal |
| issn | 0040-3660 2309-5342 |
| language | Russian |
| last_indexed | 2024-12-14T09:44:00Z |
| publishDate | 2009-03-01 |
| publisher | "Consilium Medicum" Publishing house |
| record_format | Article |
| series | Терапевтический архив |
| spelling | doaj.art-bcc22a54c53a4da28f60894fee3f0e4f2022-12-21T23:07:43Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422009-03-01813545727326Arterial stiffness and risk factors of cardiovascular diseaseA P RebrovN M NikitinaN A KaroliN A MagdeevaI A KharitonovaD A KondakovaA P RebrovN M NikitinaN A KaroliN A MagdeevaI A KharitonovaD A KondakovaAim. To investigate arterial stiffness (AS) in healthy subjects and its correlation with standard cardiovascular risk factors (CRF). Material and methods. AS was estimated on Tensioclinic arteriograph (Tensiomed, Hungary) in 97 subjects (76 females and 21 males) having symptoms of neither atherosclerosis nor coronary heart disease (CHD). Detection of CRF was made by questionnaire survey. 10-year CHD risk and cardiovascular death risk (SCORE) were estimated. Results. With age, there was a rise of augmentation index (AI) (r = 0.76; p < 0.001) and pulse wave velocity (PWV) in the aorta (r = 0.61; p < 0.001), AI changes arose earlier than those of aortic PWV. Arterial hypertension is an independent factor of arterial stiffness deterioration. High blood cholesterol, AS, body mass index, smoking index directly correlate with AI and PWV in young subjects. CHD risk and SCORE rise with an AS increase (r = 0.30; p < 0.05 and r = 0.34; p < 0.05, respectively). Conclusion. Of CRF, most significant determinant of AS are arterial hypertension and age. AI is a more sensitive marker of AS in young subjects. Increased aortic PWV is more typical for persons over 50 years of age. The study of pulse wave characteristics with application of Tensioclinic arteriograph is a simple and significant method of detecting early changes in AS.https://ter-arkhiv.ru/0040-3660/article/view/30299arterial stiffnessarteriographaugmentation indexpulse wave velocitycardiovascular risk |
| spellingShingle | A P Rebrov N M Nikitina N A Karoli N A Magdeeva I A Kharitonova D A Kondakova A P Rebrov N M Nikitina N A Karoli N A Magdeeva I A Kharitonova D A Kondakova Arterial stiffness and risk factors of cardiovascular disease Терапевтический архив arterial stiffness arteriograph augmentation index pulse wave velocity cardiovascular risk |
| title | Arterial stiffness and risk factors of cardiovascular disease |
| title_full | Arterial stiffness and risk factors of cardiovascular disease |
| title_fullStr | Arterial stiffness and risk factors of cardiovascular disease |
| title_full_unstemmed | Arterial stiffness and risk factors of cardiovascular disease |
| title_short | Arterial stiffness and risk factors of cardiovascular disease |
| title_sort | arterial stiffness and risk factors of cardiovascular disease |
| topic | arterial stiffness arteriograph augmentation index pulse wave velocity cardiovascular risk |
| url | https://ter-arkhiv.ru/0040-3660/article/view/30299 |
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