The Altered Somatic Brain Network in State Anxiety
Highly anxious individuals often show excessive emotional arousal, somatic arousal, and characteristics of mental illness. Previous researches have extensively investigated the emotional and cognitive biases of individuals with high anxiety, but overlooked the spontaneous brain activity and function...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2019-07-01
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| Series: | Frontiers in Psychiatry |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fpsyt.2019.00465/full |
| _version_ | 1818363679289114624 |
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| author | Xianrui Li Meng Zhang Meng Zhang Kun Li Feng Zou Yufeng Wang Xin Wu Hongxing Zhang Hongxing Zhang Hongxing Zhang |
| author_facet | Xianrui Li Meng Zhang Meng Zhang Kun Li Feng Zou Yufeng Wang Xin Wu Hongxing Zhang Hongxing Zhang Hongxing Zhang |
| author_sort | Xianrui Li |
| collection | DOAJ |
| description | Highly anxious individuals often show excessive emotional arousal, somatic arousal, and characteristics of mental illness. Previous researches have extensively investigated the emotional and cognitive biases of individuals with high anxiety, but overlooked the spontaneous brain activity and functional connections associated with somatic arousal. In this study, we investigated the relationship between state anxiety and the spontaneous brain activity of the somatosensory cortex in a non-clinical healthy population with state anxiety. Furthermore, we also explored the functional connections of the somatosensory cortex. We found that state anxiety was positively correlated with the amplitude of low-frequency fluctuations (ALFFs) of somatic related brain regions, including the right postcentral gyrus (somatosensory cortex) and the right precentral gyrus (somatic motor cortex). Furthermore, we found that state anxiety was positively correlated with the connections between the postcentral gyrus and the left cerebellum gyrus, whereas state anxiety was negatively correlated with the connectivity between the postcentral gyrus and brain regions including the left inferior frontal cortex and left medial superior frontal cortex. These results revealed the association between the anxious individuals’ body-loop and state anxiety in a healthy population, which revealed the importance of somatic brain regions in anxiety symptoms and provided a new perspective on anxiety for further study. |
| first_indexed | 2024-12-13T21:52:18Z |
| format | Article |
| id | doaj.art-bcc6a765996a4aedac2f7dc64893446a |
| institution | Directory Open Access Journal |
| issn | 1664-0640 |
| language | English |
| last_indexed | 2024-12-13T21:52:18Z |
| publishDate | 2019-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychiatry |
| spelling | doaj.art-bcc6a765996a4aedac2f7dc64893446a2022-12-21T23:30:13ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402019-07-011010.3389/fpsyt.2019.00465466309The Altered Somatic Brain Network in State AnxietyXianrui Li0Meng Zhang1Meng Zhang2Kun Li3Feng Zou4Yufeng Wang5Xin Wu6Hongxing Zhang7Hongxing Zhang8Hongxing Zhang9School of Psychology, Xinxiang Medical University, Xinxiang, ChinaSchool of Psychology, Xinxiang Medical University, Xinxiang, ChinaDepartment of Psychiatry, Henan Mental Hospital, The Second Affiliated Hospital of Xinxiang Medical University, Xinxiang, ChinaDepartment of Psychiatry, Henan Mental Hospital, The Second Affiliated Hospital of Xinxiang Medical University, Xinxiang, ChinaSchool of Psychology, Xinxiang Medical University, Xinxiang, ChinaSchool of Psychology, Xinxiang Medical University, Xinxiang, ChinaSchool of Psychology, Xinxiang Medical University, Xinxiang, ChinaSchool of Psychology, Xinxiang Medical University, Xinxiang, ChinaDepartment of Psychiatry, Henan Mental Hospital, The Second Affiliated Hospital of Xinxiang Medical University, Xinxiang, ChinaHenan key Laboratory of Biological Psychiatry, Xinxiang, ChinaHighly anxious individuals often show excessive emotional arousal, somatic arousal, and characteristics of mental illness. Previous researches have extensively investigated the emotional and cognitive biases of individuals with high anxiety, but overlooked the spontaneous brain activity and functional connections associated with somatic arousal. In this study, we investigated the relationship between state anxiety and the spontaneous brain activity of the somatosensory cortex in a non-clinical healthy population with state anxiety. Furthermore, we also explored the functional connections of the somatosensory cortex. We found that state anxiety was positively correlated with the amplitude of low-frequency fluctuations (ALFFs) of somatic related brain regions, including the right postcentral gyrus (somatosensory cortex) and the right precentral gyrus (somatic motor cortex). Furthermore, we found that state anxiety was positively correlated with the connections between the postcentral gyrus and the left cerebellum gyrus, whereas state anxiety was negatively correlated with the connectivity between the postcentral gyrus and brain regions including the left inferior frontal cortex and left medial superior frontal cortex. These results revealed the association between the anxious individuals’ body-loop and state anxiety in a healthy population, which revealed the importance of somatic brain regions in anxiety symptoms and provided a new perspective on anxiety for further study.https://www.frontiersin.org/article/10.3389/fpsyt.2019.00465/fullstate anxietysomatic marker hypothesissomatosensory cortexpostcentral gyrusresting-state functional magnetic resonance imaging |
| spellingShingle | Xianrui Li Meng Zhang Meng Zhang Kun Li Feng Zou Yufeng Wang Xin Wu Hongxing Zhang Hongxing Zhang Hongxing Zhang The Altered Somatic Brain Network in State Anxiety Frontiers in Psychiatry state anxiety somatic marker hypothesis somatosensory cortex postcentral gyrus resting-state functional magnetic resonance imaging |
| title | The Altered Somatic Brain Network in State Anxiety |
| title_full | The Altered Somatic Brain Network in State Anxiety |
| title_fullStr | The Altered Somatic Brain Network in State Anxiety |
| title_full_unstemmed | The Altered Somatic Brain Network in State Anxiety |
| title_short | The Altered Somatic Brain Network in State Anxiety |
| title_sort | altered somatic brain network in state anxiety |
| topic | state anxiety somatic marker hypothesis somatosensory cortex postcentral gyrus resting-state functional magnetic resonance imaging |
| url | https://www.frontiersin.org/article/10.3389/fpsyt.2019.00465/full |
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